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1. (WO1998051679) TOCOPHEROL ESTERS AND THEIR COSMETIC AND PHARMACEUTICAL USES

Pub. No.:    WO/1998/051679    International Application No.:    PCT/FR1998/000958
Publication Date: Fri Nov 20 00:59:59 CET 1998 International Filing Date: Fri May 15 01:59:59 CEST 1998
IPC: A61K 8/67
C07D 311/72
Applicants: LVMH RECHERCHE
BONTE, Frédéric
SAUNOIS, Alex
Inventors: BONTE, Frédéric
SAUNOIS, Alex
Title: TOCOPHEROL ESTERS AND THEIR COSMETIC AND PHARMACEUTICAL USES
Abstract:
The invention concerns an ester characterised in that it has the chemical formula (I) below in its dl or d form in which: R1, R2 and R3 represent independently a hydrogen atom, a methyl radical; A represents the groups (a), or (b), R4 and R5, identical or different, represent each a chain formation in the form: -Bm-Cn-Bp-Cq-H in which B is a group (c), C is a group (d), and each of the indices m, n, p, and q is a whole number between 0 and 4, the sum m +n + p+ q being restricted to whole numbers between 0 to 4. The ester is useful for preparing cosmetic or pharmaceutical compositions, in particular dermatological with anti-radical, anti-inflammatory activity, promoting the differentiation of keratocytes, improving skin hydration and fineness of skin texture, with anti-ageing or depigmentation action.