Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO1998051667) INDOLE DERIVATIVES AND MONO- AND DIAZAINDOLE DERIVATIVES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051667 International Application No.: PCT/JP1998/002139
Publication Date: 19.11.1998 International Filing Date: 15.05.1998
Chapter 2 Demand Filed: 05.06.1998
IPC:
C07D 209/08 (2006.01) ,C07D 471/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
209
Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
condensed with one carbocyclic ring
04
Indoles; Hydrogenated indoles
08
with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
CHUGAI SEIYAKU KABUSHIKI KAISHA [JP/JP]; 5-1, Ukima 5-chome Kita-ku Tokyo 115-8543, JP (AllExceptUS)
MATSUOKA, Hiroharu [JP/JP]; JP (UsOnly)
MARUYAMA, Noriaki [JP/JP]; JP (UsOnly)
KASHIWAGI, Hirotaka [JP/JP]; JP (UsOnly)
Inventors:
MATSUOKA, Hiroharu; JP
MARUYAMA, Noriaki; JP
KASHIWAGI, Hirotaka; JP
Agent:
TSUKUNI, Hajime; SVAX TS Building 22-12, Toranomon 1-chome Minato-ku Tokyo 105-0001, JP
Priority Data:
9/12705916.05.1997JP
Title (EN) INDOLE DERIVATIVES AND MONO- AND DIAZAINDOLE DERIVATIVES
(FR) DERIVES D'INDOLE ET DERIVES DE MONO- ET DIAZAINDOLE
Abstract:
(EN) Compounds represented by general formula (I), wherein A1 represents =N-, etc.; A2 represents =N- or =CH-; R1 represents hydrogen, etc.; R3 represents an alkyl, etc.; R4 represents an optionally substituted aryl, etc., hydrates thereof, and pharmaceutically acceptable salts of both. These compounds have COX-2 inhibitory activities and are useful as medicines such as an antiphlogistic.
(FR) L'invention concerne des composés de formule générale (I). Dans ladite formule, A1 est =N- etc.; A2 est =N- ou =CH-; R1 est hydrogène etc; R3 est alkyle etc.; R4 est aryle éventuellement substitué etc. On décrit lesdits composés, leurs hydrates et sels pharmaceutiquement acceptables. Ces composés ont une action inhibitrice sur COX-2 et sont utiles comme médicaments, par exemple du type antiphlogistique.
front page image
Designated States: AL, AU, BA, BB, BG, BR, CA, CN, CU, CZ, EE, GE, GW, HU, ID, IL, IS, KR, LC, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, SL, TR, TT, UA, US, UZ, VN, YU
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
AU1998072379