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Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/051326 International Application No.: PCT/IB1998/000863
Publication Date: 19.11.1998 International Filing Date: 15.05.1998
Chapter 2 Demand Filed: 16.12.1998
IPC:
A61K 38/16 (2006.01) ,G01N 33/574 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
Applicants: HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP[CA/CA]; 555 University Avenue Toronto, Ontario M5G 1X8, CA
Inventors: ARAB, Sara; CA
LINGWOOD, Clifford, A.; CA
Agent: FRITZ, Joachim, T. ; Scott & Aylen Suite 1000 60 Queen Street Ottawa, Ontario K1P 5Y7, CA
Priority Data:
60/046,64016.05.1997US
Title (EN) INHIBITION OF ANGIOGENESIS BY VEROTOXINS
(FR) INHIBITION DE L'ANGIOGENESE AU MOYEN DE VEROTOXINES
Abstract:
(EN) The invention pertains to methods for inhibiting angiogenesis. Diagnostic and therapeutic methods utilizing anti-angiogenic agents which bind Gb3 or CD77, e.g., verotoxins, are provided. Methods for treating multiple drug resistant tumors are also provided.
(FR) L'invention, qui a trait à des méthodes visant à l'inhibition de l'angiogenèse, concerne des méthodes diagnostiques et thérapeutiques faisant intervenir des agents angiogéniques fixant Gb3 ou CD77, des vérotoxines notamment. Elle porte également sur des méthodes de traitement de tumeurs dotées d'une résistance multiple aux anti-cancéreux.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)