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1. (WO1998051323) NOVEL ANTIANGIOGENIC PEPTIDE AGENTS AND THEIR THERAPEUTIC AND DIAGNOSTIC USE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051323 International Application No.: PCT/US1998/009691
Publication Date: 19.11.1998 International Filing Date: 12.05.1998
Chapter 2 Demand Filed: 10.12.1998
IPC:
A61K 38/00 (2006.01) ,C07K 14/575 (2006.01) ,C07K 14/61 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
61
Growth hormone (GH) (Somatotropin)
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 12th floor 1111 Franklin Street Oakland, CA 94607-5200, US (AllExceptUS)
WEINER, Richard, I. [US/US]; US (UsOnly)
MARTIAL, Joseph, A. [BE/BE]; BE (UsOnly)
STRUMAN, Ingrid [BE/BE]; BE (UsOnly)
TAYLOR, Robert [US/US]; US (UsOnly)
BENTZIEN, Frauke; US (UsOnly)
Inventors:
WEINER, Richard, I.; US
MARTIAL, Joseph, A.; BE
STRUMAN, Ingrid; BE
TAYLOR, Robert; US
BENTZIEN, Frauke; US
Agent:
ASHTON, Nina, M. ; Cooley Godward LLP 5 Palo Alto Square 3000 El Camino Real Palo Alto, CA 94306-2155, US
Priority Data:
60/046,39413.05.1997US
Title (EN) NOVEL ANTIANGIOGENIC PEPTIDE AGENTS AND THEIR THERAPEUTIC AND DIAGNOSTIC USE
(FR) NOUVEAUX AGENTS PEPTIDIQUES ANTI-ANGIOGENIQUES, UTILISATION DE CES DERNIERS POUR LA THERAPIE ET LE DIAGNOSTIC
Abstract:
(EN) The current invention concerns novel antiangiogenic peptides which correspond to about 10 to about 150 consecutive amino acids of N-terminal sequence of human growth hormone, human placental lactogen, human growth hormone variant hGH-V, and prolactin, and their use in inhibiting angiogenesis and in the diagnosis of diseases of human pregnancy involving abnormalities of placental vascularization.
(FR) Cette invention concerne de nouveaux peptides anti-angiogéniques qui correspondent approximativement à 10 à 150 aminoacides consécutifs de séquences N-terminales de l'hormone de croissance humaine, de lactogène placentaire U20, du variant hGH-V de l'hormone de croissance humaine et de la prolactine, ainsi que leur utilisation pour inhiber l'angiogènese et pour le diagnostic de maladie de la grossesse chez la femme qui implique des anomalies de la vascularisation du placenta.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1173191AU1998073832