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1. (WO1998051313) REMEDIES FOR DRY EYE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051313 International Application No.: PCT/JP1998/002080
Publication Date: 19.11.1998 International Filing Date: 12.05.1998
Chapter 2 Demand Filed: 12.10.1998
IPC:
A61K 31/59 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
59
Compounds containing 9,10-seco-cyclopenta[a]hydro- phenanthrene ring systems
Applicants:
SANTEN PHARMACEUTICAL CO., LTD. [JP/JP]; 9-19, Shimoshinjo 3-chome Higashiyodogawa-ku Osaka-shi Osaka 533-8651, JP (AllExceptUS)
TEIJIN LIMITED [JP/JP]; 6-7, Minamihommachi 1-chome Chuo-ku Osaka-shi Osaka 541-8587, JP (AllExceptUS)
NAKATA, Katsuhiko [JP/JP]; JP (UsOnly)
NAKAMURA, Masatsugu [JP/JP]; JP (UsOnly)
HAZATO, Atsuo [JP/JP]; JP (UsOnly)
Inventors:
NAKATA, Katsuhiko; JP
NAKAMURA, Masatsugu; JP
HAZATO, Atsuo; JP
Agent:
KISHIMOTO, Einosuke ; Inaba Building 3rd floor 13-18, Nishishinsaibashi 1-chome Chuo-ku Osaka-shi Osaka 542-0086, JP
Priority Data:
9/12675916.05.1997JP
Title (EN) REMEDIES FOR DRY EYE
(FR) REMEDES CONTRE LES YEUX SECS
Abstract:
(EN) Novel effects and medicinal uses of 1$g(a),24-dihydroxylated vitamin D3, that is, (1) remedies for dry eye, (2) differentiation inhibitors for cornified corneal epithelial cells, and (3) transglutaminase I (TG-I) expression inhibitors, each containing 1$g(a),24-dihydroxylated vitamin D3 as the active ingredient.
(FR) Cette invention concerne de nouveaux effets et de nouvelles utilisations médicales de la vitamine D3 1$g(a),24-dihydroxylée, qui sert à produire: (1) des remèdes contre les yeux secs, (2) des inhibiteurs de différenciation pour les cellules épithéliales cornéennes kératinisées, et (3) des inhibiteurs d'expression de la transglutaminase I (TG-1), ces agents contenant tous de la vitamine D3 1$g(a),24-dihydroxylée comme principe actif.
Designated States: CA, CN, KR, NO, US
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
EP0998931