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1. (WO1998051306) MEDICINAL COMPOSITIONS AGAINST HELICOBACTER PYLORI
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051306 International Application No.: PCT/JP1998/002133
Publication Date: 19.11.1998 International Filing Date: 14.05.1998
Chapter 2 Demand Filed: 19.08.1998
IPC:
A61K 31/47 (2006.01) ,C07D 215/60 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
215
Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
58
with hetero atoms directly attached to the ring nitrogen atom
60
N-oxides
Applicants:
YAMANOUCHI PHARMACEUTICAL CO., LTD. [JP/JP]; 3-11, Nihonbashi-Honcho 2-chome Chuo-ku Tokyo 103-8411, JP (AllExceptUS)
P.T.KALBE FARMA [ID/ID]; Jalan Jendral Ahmad Yani (Pulo Mas) 13210 Jakarta Timur, ID (AllExceptUS)
WATANABE, Masato [JP/JP]; JP (UsOnly)
TANAKA, Kouichi [JP/JP]; JP (UsOnly)
KOMIYA, Masayuki [JP/JP]; JP (UsOnly)
RANTIATMODJO, Ratna, Murni [ID/ID]; ID (UsOnly)
Inventors:
WATANABE, Masato; JP
TANAKA, Kouichi; JP
KOMIYA, Masayuki; JP
RANTIATMODJO, Ratna, Murni; ID
Agent:
NAGAI, Shozo ; Yamanouchi Pharmaceutical Co., Ltd. Patent & Information Dept. 17-1, Hasune 3-chome Itabashi-ku Tokyo 174-8612, JP
Priority Data:
9/12746216.05.1997JP
Title (EN) MEDICINAL COMPOSITIONS AGAINST HELICOBACTER PYLORI
(FR) COMPOSITIONS MEDICAMENTEUSES CONTRE L'$i(HELICOBACTER PYLORI)
Abstract:
(EN) Medicinal compositions against $i(Helicobacter pylori), which contain as the active ingredient a 1-hydroxy-3-methyl-quinolone derivative represented by formula (I) or its pharmaceutically acceptable salt. Because of having an antibacterial effect on $i(H. pylori), the above compound is useful in treating or preventing infection of human beings with $i(H. pylori) and infections of animals with bacteria belonging to the genus $i(Helicobacter) in relation thereto. The above compositions are useful in the prevention (including the prevention of recurrence) and treatment of peptic ulcers (gastric ulcer, duodenal ulcer, etc.), inflammations (acute or chronic gastritis or duodenitis), diseases in the upper part of the digestive tract (gastric cancer, etc.), mucosa-associated lymphoid tissue (MALT) lymphoma, chronic heart diseases, etc.
(FR) L'invention porte sur des compositions médicamenteuses contre l'$i(Helicobacter pylori) dont le principe actif est un dérivé de la 1-hydroxy-3-méthylquinolone représenté par la formule (I) suivante, ou ses sels pharmacocompatibles. En raison de son pouvoir antibactérien sur l'$i(Helicobacter pylori), le composé ci-dessus peut traiter ou prévenir chez l'homme les infections dues à l'$i(Helicobacter pylori), et chez l'animal, les infections par des bactéries du genre $i(Helicobacter). Les compositions ci-dessus peuvent notamment être utilisées pour la prévention (y compris la prévention des récidives) et le traitement des ulcères gastroduodénaux (etc.), des inflammations (gastrites aiguës ou chroniques ou duodénites), des maladies des voies digestives supérieures (cancer gastrique, etc.), des lymphomes des tissus lymphoïdes associés aux muqueuses, des maladies cardiaques chroniques, etc.
front page image
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, GH, GW, HU, ID, IL, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, RO, RU, SD, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
KR1020010012572EP0992241US6184230CN1255853CA2290549AU1998072376