Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1998051299) PATCHES CONTAINING ISOSORBIDE NITRATE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051299 International Application No.: PCT/JP1998/002062
Publication Date: 19.11.1998 International Filing Date: 11.05.1998
IPC:
A61K 9/70 (2006.01) ,A61K 31/34 (2006.01) ,A61K 47/32 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
70
Web, sheet or filament bases
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
34
having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
32
Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
Applicants:
TEIKOKU SEIYAKU CO., LTD. [JP/JP]; 567, Sanbonmatsu Ohchicho Ohkawa-gun Kagawa 769-2601, JP (AllExceptUS)
KAWAJI, Toshikuni [JP/JP]; JP (UsOnly)
YAMAJI, Masahiro [JP/JP]; JP (UsOnly)
Inventors:
KAWAJI, Toshikuni; JP
YAMAJI, Masahiro; JP
Agent:
KUSAMA, Osamu; Iwata Building 7th floor 5-12, Iidabashi 4-chome Chiyoda-ku Tokyo 102-0072, JP
Priority Data:
9/13575112.05.1997JP
Title (EN) PATCHES CONTAINING ISOSORBIDE NITRATE
(FR) PATCHS CONTENANT DU NITRATE D'ISOSORBIDE
Abstract:
(EN) Patches containing isosorbide nitrate, having sufficient tackiness in the application thereof, and stabilized in the release of the drug after the application. The patches are characterized in that isosorbide nitrate is added as the active ingredient to tacky plasters containing as the essential ingredients styrene-isoprene-styrene block copolymers, rosin resins, liquid rubbers, antioxidants and oleic acid. More particularly, 15 to 25 % (w/w) of isosorbide nitrate is added to plasters containing 15 to 35 % of styrene-isoprene-styrene block copolymers, 35 to 55 % of rosin resins, 5 to 20 % of liquid rubbers, 0.1 to 2 % of antioxidants and 0.1 to 5 % of oleic acid.
(FR) L'invention concerne des patchs contenant du nitrate d'isosorbide, qui sont suffisamment collants lorsqu'ils sont appliqués et stabilisés pour ce qui concerne la libération du médicament après leur application. Les patchs de l'invention se caractérisent en ce que du nitrate d'isosorbide est ajouté en tant que principe actif à l'emplâtre collant contenant, comme ingrédients principaux, des copolymères blocs styrène-isoprène-styrène, des colophanes, des caoutchoucs liquides, des antioxydants et de l'acide oléique. Plus particulièrement 15 à 25 % en poids de nitrate d'isosorbide est ajouté aux emplâtres contenant 15 à 35 % de copolymères blocs styrene-isoprène-styrène, 35 à 55 % de colophanes, 5 à 20 % de caoutchoucs liquides, 0,1 à 2 % d'antioxydants et 0,1 à 5 % d'acide oléique.
Designated States: AU, CA, US
European Patent Office (BE, DE, FR, GB, IT, NL)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
EP0968713US6231884CA2259584AU1998072353