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1. (WO1998051294) METHOD AND COMPOSITION FOR TREATING CANCERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051294 International Application No.: PCT/US1998/009703
Publication Date: 19.11.1998 International Filing Date: 14.05.1998
Chapter 2 Demand Filed: 23.11.1998
IPC:
A61K 31/045 (2006.01) ,A61K 31/047 (2006.01) ,A61K 31/122 (2006.01) ,A61K 31/15 (2006.01) ,A61K 31/16 (2006.01) ,A61K 31/19 (2006.01) ,A61K 31/196 (2006.01) ,A61K 31/215 (2006.01) ,A61K 31/235 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
045
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
045
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
047
having two or more hydroxy groups, e.g. sorbitol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
12
Ketones
122
having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
15
Oximes (CN-O-); Hydrazines (N-N); Hydrazones (N-N)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
196
the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
235
having an aromatic ring attached to a carboxyl group
Applicants:
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS [US/US]; 352 Administration Building 506 South Wright Street Urbana, IL 61801, US
Inventors:
PEZZUTO, John, M.; US
DASGUPTA, Tapas, K.; US
KIM, Darrick, S., H., L.; US
SCHMIDT, Mary, Lou; US
KUZMANOFF, Konrad, Marc; US
LING-INDECK, Lydia; US
Agent:
NAPOLI, James, J.; Marshall, O'Toole, Gerstein, Murray & Borun Suite 6300 233 South Wacker Drive Chicago, IL 60606, US
Priority Data:
08/857,41316.05.1997US
Title (EN) METHOD AND COMPOSITION FOR TREATING CANCERS
(FR) PROCEDE ET COMPOSITION DE TRAITEMENT ANTI-CANCER
Abstract:
(EN) A composition and method of preventing or inhibiting tumor growth, and of treating malignant cancers without toxic side effects are disclosed. Betulinic acid or a betulinic acid derivative is the active compound of the composition.
(FR) L'invention concerne une composition et un procédé permettant d'éviter ou d'inhiber la croissance de tumeurs, et de traiter des tumeurs malignes sans effets secondaires toxiques. Le composé actif de la composition est l'acide bétulinique ou un dérivé d'acide bétulinique.
Designated States: CA, JP, MX
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0981342EP1495754CA2289684