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1. (WO1998051291) USE OF A PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING ISCHEMIA
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051291 International Application No.: PCT/BE1998/000067
Publication Date: 19.11.1998 International Filing Date: 12.05.1998
Chapter 2 Demand Filed: 16.10.1998
IPC:
A61K 31/175 (2006.01) ,A61K 31/341 (2006.01) ,A61K 31/365 (2006.01) ,A61K 31/37 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
17
having the group N-C(O)-N or N-C(S)-N, e.g. urea, thiourea, carmustine
175
having the group , N-C(O)-NN- or , e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
34
having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
341
not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
365
Lactones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
365
Lactones
366
having six-membered rings, e.g. delta-lactones
37
Coumarins, e.g. psoralen
Applicants:
REMACLE, José [BE/BE]; BE
MICHIELS, Carine [BE/BE]; BE (UsOnly)
Inventors:
REMACLE, José; BE
MICHIELS, Carine; BE
Agent:
VAN MALDEREN, Eric ; Office Van Malderen Place Reine Fabiola 6/1 B-1083 Bruxelles, BE
Priority Data:
970041513.05.1997BE
Title (EN) USE OF A PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING ISCHEMIA
(FR) UTILISATION D'UNE COMPOSITION PHARMACEUTIQUE DANS LE TRAITEMENT ET/OU LA PREVENTION DE L'ISCHEMIE
Abstract:
(EN) The invention concerns the use of a pharmaceutical composition comprising a suitable pharmaceutical carrier and an active compound selected among the group consisting of bioflavonoids, rutin-garlic, troxerutin, coumarin, diosmin, o-(-hydroxyethyl) rutins, sweet clover and rutin extracts, tribenoside, methylchalcone hesperidin, Indian chestnut extract, naphtazone, esculoside, aescin, procyanidine oligomers, butcher's broom and methylchalcone hesperidine extracts, ruscosides, common holly and black currant extracts, blueberry anthocyanin extracts, the active principles of these compounds and/or a mixture of them, acting on a patient's mitochondrial membrane protein complexes, to prepare a medicine for treating and/or preventing ischemia and/or pathologies associated with ischemia or with energy deficiency.
(FR) La présente invention concerne l'utilisation d'une composition pharmaceutique comprenant un véhicule pharmaceutique adéquat et un composé actif choisi parmi le groupe constitué par les citroflavonoïdes, l'ail-rutoside, la troxérutine, la coumarine, la diosmine, les o-(-hydroxyéthyl) rutosides, les extraits de Mélilot et de rutoside, le tribénoside, l'hespéridine méthylchalcone, l'extrait de marron d'Inde, le naftazone, l'esculoside, l'aescine, les oligomères procyanidoliques, les extraits de ruscus et d'hespéridine méthylchalcone, les ruscosides, les extraits de petit houx et cassis, les extraits d'anthocyanodisiques de myrtilles, les principes actifs de ces composés et/ou mélange d'entre eux, agissant sur les complexes protéiniques de la membrane mitochondriale interne d'un patient, pour la préparation d'un médicament destiné au traitement et/ou à la prévention de l'ischémie et/ou des pathologies associées à l'ischémie ou à un déficit énergétique.
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Designated States: AL, AU, BA, BB, BG, BR, CA, CN, CU, CZ, DE, EE, GE, GW, HU, ID, IL, IS, JP, KP, KR, LC, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, SL, TR, TT, UA, US, UZ, VN, YU
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
NO19995500EP0981339JP2001526658 CA2287363AU1998073272