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1. (WO1998051281) AQUEOUS SUSPENSION PREPARATIONS WITH EXCELLENT REDISPERSIBILITY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/051281 International Application No.: PCT/JP1998/001998
Publication Date: 19.11.1998 International Filing Date: 30.04.1998
Chapter 2 Demand Filed: 08.10.1998
IPC:
A61K 9/00 (2006.01) ,A61K 9/08 (2006.01) ,A61K 47/32 (2006.01) ,A61K 47/38 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
32
Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
38
Cellulose; Derivatives thereof
Applicants:
SENJU PHARMACEUTICAL CO., LTD. [JP/JP]; 5-8, Hiranomachi 2-chome Chuo-ku Osaka-shi Osaka 541-0046, JP (AT, BE, CA, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, KR, LU, MC, NL, PT, SE)
YASUEDA, Shin-ichi [JP/JP]; JP (UsOnly)
MATSUHISA, Keiichi [JP/JP]; JP (UsOnly)
TERAYAMA, Hideo [JP/JP]; JP (UsOnly)
INADA, Katsuhiro [JP/JP]; JP (UsOnly)
Inventors:
YASUEDA, Shin-ichi; JP
MATSUHISA, Keiichi; JP
TERAYAMA, Hideo; JP
INADA, Katsuhiro; JP
Priority Data:
9/12416614.05.1997JP
Title (EN) AQUEOUS SUSPENSION PREPARATIONS WITH EXCELLENT REDISPERSIBILITY
(FR) PREPARATIONS A BASE DE SUSPENSIONS AQUEUSES POSSEDANT D'EXCELLENTES PROPRIETES DE REDISPERSION
Abstract:
(EN) A aqueous suspension preparations of hardly soluble drugs containing water soluble polymers at a concentration within a range from the concentration at which the decrease in the surface tension of the liquid preparations is initiated to the concentration at which such decrease is terminated. These preparations can be easily redispersed and undergo neither aggregation of the dispersed particles nor caking. The excellent redispersibility of these preparations makes them useful as injections, eye drops, nasal drops, drugs for internal use, lotions, etc.
(FR) L'invention concerne des préparations à base de suspensions aqueuses utilisant des médicaments à peine solubles qui comprennent des polymères hydrosolubles dont la concentration est comprise entre, d'une part, une valeur qui correspond au début d'une baisse de la tension superficielle des préparations liquides et, d'autre part, une valeur à laquelle cette baisse prend fin. Ces préparations sont aptes à une redispersion aisée et ne subissent ni d'agglutination, ni d'agrégation des particules dispersées. Les excellentes propriétés de redispersion de ces préparations permettent de les utiliser en tant qu'injections, collyres, gouttes pour le nez, médicaments pour l'usage interne, lotions, etc.
Designated States: CA, KR, US
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
KR1020010012188EP0995435US20010036966US6274634US20030008010CA2289618