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1. (WO1998051260) USE OF D-ARGININE AND/OR L-ARGININE TO PROTECT THE AMINO GROUPS OF BIOLOGICAL SUBSTANCES FROM DAMAGE, INACTIVATION, OR MODIFICATION BY TOXIC CARBONYLS AND/OR DICARBONYLS
Latest bibliographic data on file with the International Bureau

Considered void 11.08.1999


Pub. No.: WO/1998/051260 International Application No.: PCT/US1998/010057
Publication Date: 19.11.1998 International Filing Date: 14.05.1998
IPC:
A61K 35/14 (2006.01) ,A61K 35/16 (2006.01) ,A61K 38/04 (2006.01) ,A61K 38/38 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
14
Blood
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
14
Blood
16
Plasma; Serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
38
Albumins
Applicants:
REDOX, INC. [US/US]; 296 Audubon Boulevard New Orleans, LA 70125, US (AllExceptUS)
HAIK, George, M., Jr. [US/US]; US (UsOnly)
Inventors:
HAIK, George, M., Jr.; US
Agent:
NEHRBASS, Seth, M.; Pravel, Hewitt, Kimball & Krieger 10th floor 1177 West Loop South Houston, TX 77027, US
Priority Data:
60/046,43014.05.1997US
60/059,42031.07.1997US
Title (EN) USE OF D-ARGININE AND/OR L-ARGININE TO PROTECT THE AMINO GROUPS OF BIOLOGICAL SUBSTANCES FROM DAMAGE, INACTIVATION, OR MODIFICATION BY TOXIC CARBONYLS AND/OR DICARBONYLS
(FR) UTILISATION DE D-ARGININE ET/OU DE L-ARGININE POUR PROTEGER LES GROUPES AMINO DE SUBSTANCES BIOLOGIQUES CONTRE LES DOMMAGES, L'INACTIVATION OU LA MODIFICATION PROVOQUEES PAR DES CARBONYLES ET/OU DICARBONYLES TOXIQUES
Abstract:
(EN) A method of blocking dicarbonyls and carbonyls $i(in vitro) and $i(in vivo) includes using an effective quantity of an L- or D-arginine, substituted arginine, modified arginine or arginine-containing blocking agent. The method can, for example, include blocking toxic dicarbonyls and carbonyls in a patient suffering from a condition associated with toxic carbonyls and/or dicarbonyls, by administering to the patient a therapeutically effective dose of an L- or D-arginine, substituted arginine, modified arginine or arginine-containing blocking agent.
(FR) Procédé de blocage de dicarbonyles et de carbonyles $i(in vitro) et $i(in vivo) qui consiste à utiliser une quantité efficace de D- ou L-arginine, d'arginine substituée, d'arginine modifiée ou d'un agent de blocage contenant de l'arginine. Ledit procédé peut par exemple consister à bloquer des dicarbonyles et carbonyles toxiques chez un patient souffrant d'une pathologie associée aux carbonyles et/ou dicarbonyles toxiques en administrant à ce patient une dose efficace sur le plan thérapeutique d'une L- ou D-arginine, d'une arginine substituée, d'une arginine modifiée ou d'un agent de blocage contenant de l'arginine.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1998075752