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1. (WO1998050547) HUMAN TOLL-LIKE RECEPTOR PROTEINS, RELATED REAGENTS AND METHODS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/050547 International Application No.: PCT/US1998/008979
Publication Date: 12.11.1998 International Filing Date: 07.05.1998
Chapter 2 Demand Filed: 21.10.1998
IPC:
C07K 14/705 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
Applicants:
SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, NJ 07033, US
Inventors:
HARDIMAN, Gerard, T.; US
ROCK, Fernando, L.; US
BAZAN, J., Fernando; US
KASTELEIN, Robert, A.; US
Agent:
McLAUGHLIN, Jaye, P. ; Schering-Plough Corporation Patent Dept. K-6-1 1990 2000 Galloping Hill Road Kenilworth, NJ 07033-0530, US
Priority Data:
60/044,29307.05.1997US
60/072,21222.01.1998US
60/076,94705.03.1998US
Title (EN) HUMAN TOLL-LIKE RECEPTOR PROTEINS, RELATED REAGENTS AND METHODS
(FR) RECEPTEUR PROTEIQUE HUMAIN DU TYPE TOLL, REACTIFS CONNEXES ET TECHNIQUES AFFERENTES
Abstract:
(EN) Nucleic acids encoding nine human receptors, designated DNAX Toll-like receptors 2-10 (DTLR2-10), homologous to the Drosophila Toll receptor and the human IL-1 receptor, purified DTLR proteins and fragments thereof, mono-/polyclonal antibodies against these receptors, and methods for diagnostic and therapeutic use.
(FR) L'invention, qui a trait à des acides nucléiques codant neuf récepteurs humains désignés comme récepteurs 2-10 DNAX du type Toll (DTLR2-10), concerne également des homologues du récepteur de la mouche drosophile Toll et du récepteur humain de l'interleukine 1, des récepteurs protéiques DTLR purifiés et leurs fragments ainsi que des anticorps, tant monoclonaux que polyclonaux, contre ces récepteurs. Elle prote, de surcroît, sur des techniques diagnostiques et thérapeutiques.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CZ, EE, GE, GW, HU, ID, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UZ, VN, YU
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CZPV1999-3762NO19995458SK146599MXPA/a/1999/010261KR1020010012323SG68218
IL132614EP0980429EP1798288EP1925666EP1988166JP2002514083
CN1263555CA2289912NZ338073AU1998071754DK0980429