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1. (WO1998050537) AMINO ACID ANALOGUE MAPS AND METHODS FOR USING AND DESIGNING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/050537 International Application No.: PCT/US1998/009274
Publication Date: 12.11.1998 International Filing Date: 06.05.1998
Chapter 2 Demand Filed: 04.12.1998
IPC:
G01N 33/68 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants: BURTON, James, A.[US/US]; US (UsOnly)
RSP AMINO ACID ANALOGUES, INC.[US/US]; Three Biotech One Innovation Drive Worcester, MA 01605, US (AllExceptUS)
Inventors: BURTON, James, A.; US
Agent: LAPPIN, Mark, G. ; Lappin & Kusmer LLP Two Hundred State Street Boston, MA 02109, US
Priority Data:
60/045,80207.05.1997US
60/049,64916.06.1997US
Title (EN) AMINO ACID ANALOGUE MAPS AND METHODS FOR USING AND DESIGNING THE SAME
(FR) ENSEMBLES D'ANALOGUES D'ACIDES AMINES ET PROCEDES D'UTILISATION ET DE CONCEPTION CORRESPONDANTS
Abstract:
(EN) The present invention involves maps of amino acid analogues each having a structure substantially isosteric with a corresponding parent amino acid selected from the group of the twenty genetically coded amino acids. Each of the analogues exhibits at least one common property. In addition or alternatively, each amino acid analogue has substantially the same conformation as a compound containing the corresponding parent amino acid without the amino acid analogue. Further, the present invention involves methods for designing and/or using the amino acid analogue maps in, for example, drug design.
(FR) La présente invention se rapporte à des ensembles d'analogues d'acides aminés, chacun desdits analogues présentant une structure sensiblement isostère à celle d'un acide aminé parent correspondant sélectionné dans le groupe de vingt acides aminés génétiquement codés. Les analogues d'un ensemble possèdent au moins une caractéristique commune. Chacun de ces analogues peut en outre posséder la même conformation qu'un composé contenant l'acide aminé parent correspondant mais pas l'analogue d'acide aminé. Cette invention se rapporte également à des procédés de conception et/ou d'utilisation de ces ensembles d'analogues d'acides aminés dans le cadre, par exemple, de conception de médicaments.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)