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1. (WO1998050344) SUBSTITUTED 3,3-DIAMINO-2-PROPENENITRILES, THEIR PREPARATION AND USE

Pub. No.:    WO/1998/050344    International Application No.:    PCT/DK1998/000176
Publication Date: Fri Nov 13 00:59:59 CET 1998 International Filing Date: Thu May 07 01:59:59 CEST 1998
IPC: C07B 61/00
C07C 255/30
C07C 255/58
C07C 317/48
C07D 207/26
C07D 211/42
C07D 211/58
C07D 213/38
C07D 213/40
C07D 213/74
C07D 213/75
C07D 217/04
C07D 217/06
C07D 223/10
C07D 239/42
C07D 295/145
C07D 521/00
Applicants: NOVO NORDISK A/S
Inventors: DÖRWALD, Florenzio, Zaragoza
HANSEN, John, Bondo
Title: SUBSTITUTED 3,3-DIAMINO-2-PROPENENITRILES, THEIR PREPARATION AND USE
Abstract:
Substituted cyanoenamines of general formula (I) wherein Z, R?1, R2 and R3¿ are defined in the description, compositions thereof and methods for preparing the compounds are described. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system.