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1. (WO1998050071) USE OF VIRUS-LIKE PARTICLES AS ADJUVANTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/050071 International Application No.: PCT/US1998/008146
Publication Date: 12.11.1998 International Filing Date: 22.04.1998
Chapter 2 Demand Filed: 22.10.1998
IPC:
A61K 39/116 (2006.01) ,A61K 39/12 (2006.01) ,A61K 39/39 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
116
Polyvalent bacterial antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
Applicants:
CHIRON CORPORATION [US/US]; 4560 Horton Street - R440 Emeryville, CA 94608, US
Inventors:
GRANOFF, Dan, M.; US
GREER, Catherine, E.; US
VAN NEST, Gary, A.; US
Agent:
HARBIN, Alisa, A.; Chiron Corporation Intellectual Property - R440 P.O. Box 8097 Emeryville, CA 94662-8097 , US
Priority Data:
60/045,26201.05.1997US
Title (EN) USE OF VIRUS-LIKE PARTICLES AS ADJUVANTS
(FR) UTILISATION DE PARTICULES DE TYPE VIRAL EN TANT QU'ADJUVANTS
Abstract:
(EN) Adjuvant formulations are provided that contain nonreplicating virus-like particles (VLPs). The VLPs can be derived from any of several viruses and are useful for enhancing the immunological response to a selected antigen, wherein the antigen is distinct from the particles.
(FR) La présente invention concerne des préparations adjuvantes qui contiennent des particules de type viral (VLP) incapables de se répliquer. On peut dériver les VLP à partir d'un virus quelconque parmi plusieurs virus; elles peuvent servir à renforcer la réaction immunologique à un antigène choisi, l'antigène étant différent des particules.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0980257JP2002508748 CA2288129NZ501308AU1998072545