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1. (WO1998050068) MASS SPECTROMETRY OF COLONIZATION FACTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/050068 International Application No.: PCT/US1998/008768
Publication Date: 12.11.1998 International Filing Date: 01.05.1998
Chapter 2 Demand Filed: 02.12.1998
IPC:
C07K 1/14 (2006.01) ,C07K 14/245 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
14
Extraction; Separation; Purification
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
24
from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
245
Escherichia (G)
Applicants:
U.S. GOVERNMENT, DEPARTMENT OF THE ARMY [US/US]; U.S. Army Medical Research & Materiel Command 504 Scott Street Fort Detrick, MD 21702-5012, US
Inventors:
CASSELS, Frederick, J.; US
PANNEL, Lewis, K.; US
Agent:
HENDRICKS, Glenna; P.O. Box 2509 Fairfax, VA 22031-2509, US
Priority Data:
60/045,51102.05.1997US
Title (EN) MASS SPECTROMETRY OF COLONIZATION FACTORS
(FR) SPECTROSCOPIE DE MASSE DE FACTEURS DE COLONISATION
Abstract:
(EN) This invention relates to the use of mass spectrometry for identifying specific colonization factors, such as fimbriae, fibrillae or pili, in a sample of Escherichia coli. The sample is disssolved in 1,1,1,3,3,3-hexafluoro-2-propanol prior to mass spectrometry analysis. This method is useful for tracking infections by differentially identifying the colonization factors produced by specific organisms.
(FR) L'invention porte sur l'emploi de la spectroscopie de masse pour identifier des facteurs spécifiques de colonisation tels que les fimbriae, les fibrillae ou les pili dans des échantillons d'Escherichia coli. A cet effet l'échantillon est dissout dans du 1,1,1,1,3,3,3-hexafluoro-2-propanol avant son analyse par spectroscopie de masse. Le procédé s'avère utile pour le dépistage d'infections par identification différentielle des facteurs de colonisation produits par des organismes spécifiques.
Designated States: CA, JP
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)