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1. (WO1998050049) PREPARATION OF FAGOPYRITOLS AND USES THEREFOR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/050049 International Application No.: PCT/US1998/009255
Publication Date: 12.11.1998 International Filing Date: 06.05.1998
Chapter 2 Demand Filed: 04.12.1998
IPC:
C07H 15/207 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15
Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
20
Carbocyclic rings
207
Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
Applicants:
CORNELL RESEARCH FOUNDATION, INC. [US/US]; Suite 105 20 Thornwood Drive Ithaca, NY 14850, US
Inventors:
OBENDORF, Ralph, L.; US
HORBOWICZ, Marcin; PL
Agent:
ROGALSKYJ, Peter ; Nixon, Hargrave, Devans & Doyle LLP Clinton Square P.O. Box 1051 Rochester, NY 14603, US
Priority Data:
60/045,92707.05.1997US
Title (EN) PREPARATION OF FAGOPYRITOLS AND USES THEREFOR
(FR) PREPARATION DE FAGOPYRITOLS ET LEURS UTILISATIONS
Abstract:
(EN) The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A2, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-$i(chiro)-inositol, at least one of which is an isolated Fagopyritol A1, isolated Fagopyritol A2, or isolated Fagopyritol B3, are also disclosed. Methods for preparing substantially pure Fagopyritol A1, Fagopyritol A2, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, or mixtures thereof from buckwheat are also described. The fagopyritols can be used to prepare pharmaceutical compositions, the administration of which can be used to treat diabetes.
(FR) La présente invention concerne un fagopyritol A1 isolé, un fagopyritol A2 isolé et un fagopyritol B3 isolé. Des compositions qui comportent deux ou plusieurs fagopyritols parmi des fagopyritols A1, A2, B1, B2, B3 et D-chiro-isonitol, dont au moins un est un fagopyritol A1 isolé, un fagopyritol A2 isolé ou un fagopyritol B3 isolé sont également décrites. La présente invention concerne en outre des procédés de préparation de fagopyritol A1, de fagopyritol A2, de fagopyritol B1, de fagopyritol B2, de fagopyritol B3 sensiblement purs ou de mélanges desdites substances à partir du sarrasin. Lesdits fagopyritols peuvent être utilisés pour préparer des compositions pharmaceutiques destinées au traitement du diabète.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1998072908