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1. (WO1998050028) MTP INHIBITORS AND FAT SOLUBLE VITAMIN THERAPEUTIC COMBINATIONS TO LOWER SERUM LIPID LEVELS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/050028 International Application No.: PCT/US1998/008269
Publication Date: 12.11.1998 International Filing Date: 23.04.1998
Chapter 2 Demand Filed: 16.11.1998
IPC:
A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
BRISTOL-MYERS SQUIBB COMPANY [US/US]; P.O. Box 4000 Princeton, NJ 08543-4000, US
Inventors:
GREGG, Richard, E.; US
WETTERAU, John, R., II; US
Agent:
RODNEY, Burton ; Bristol-Myers Squibb Company P.O. Box 4000 Princeton, NJ 08543-4000, US
Priority Data:
60/045,40501.05.1997US
Title (EN) MTP INHIBITORS AND FAT SOLUBLE VITAMIN THERAPEUTIC COMBINATIONS TO LOWER SERUM LIPID LEVELS
(FR) COMBINAISONS THERAPEUTIQUES D'INHIBITEUR DE MTP ET DE VITAMINE LIPOSOLUBLE DESTINEES A REDUIRE LES TAUX DE LIPIDES SERIQUES
Abstract:
(EN) A pharmaceutical combination formed of an MTP inhibitor and a fat soluble vitamin such as Vitamins E, A, K and/or D, and optionally another cholesterol lowering drug, is provided which is employed in a method for lowering serum lipids, cholesterol and/or triglycerides and thereby inhibiting or treating atherosclerosis, pancreatitis, hyperglycemia and/or obesity.
(FR) La présente invention concerne une combinaison pharmaceutique comprenant un inhibiteur de MTP (protéine de transfert de triglycéride microsomale) et une vitamine liposoluble telle que les vitamines E, A, K et/ou D, et, facultativement, un autre médicament permettant de réduire le cholestérol. Ladite combinaison pharmaceutique est utilisée dans un procédé destiné à réduire les taux sériques de lipides, de cholestérol et/ou de triglycérides et, ce faisant, à prévenir ou traiter l'athérosclérose, la pancréatite, l'hyperglycémie et/ou l'obésité.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1024804JP2001527551 CA2286341AU1998071559