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1. (WO1998049335) CONSTRUCT AND EXPRESSION OF A RETROVIRUS CHIMERICAL ENVELOPE BY VECTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/049335 International Application No.: PCT/FR1998/000872
Publication Date: 05.11.1998 International Filing Date: 29.04.1998
Chapter 2 Demand Filed: 16.11.1998
IPC:
A61K 38/00 (2006.01) ,C07K 14/475 (2006.01) ,C12N 15/867 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
475
Growth factors; Growth regulators
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
86
Viral vectors
867
Retroviral vectors
Applicants: WEBER, Anne[FR/FR]; FR (UsOnly)
NGUYEN, Tuan[FR/FR]; FR (UsOnly)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)[FR/FR]; 101, rue de Tolbiac F-75013 Paris, FR (AT, BE, CA, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, JP, LU, MC, NL, PT, SE)
Inventors: WEBER, Anne; FR
NGUYEN, Tuan; FR
Agent: MARTIN, Jean-Jacques ; Cabinet Regimbeau 26, avenue Kléber F-75116 Paris, FR
Priority Data:
97/0542030.04.1997FR
Title (EN) CONSTRUCT AND EXPRESSION OF A RETROVIRUS CHIMERICAL ENVELOPE BY VECTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
(FR) CONSTRUCTION ET EXPRESSION D'ENVELOPPE CHIMERIQUE DE RETROVIRUS PAR DES VECTEURS, ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
Abstract:
(EN) The invention concerns novel constructs for expressing a virus chimerical envelope protein comprising a nucleic sequence of a gene coding for a protein fused with a nucleic sequence coding for a virus transmembrane envelope protein, the vectors or viral particles containing them, the cells transformed by said viral particles and the methods for producing said viral particles. The invention also concerns the use of said viral particles for preparing a medicine for treating and/or preventing of diseases capable of being treated by gene therapy and the pharmaceutical compositions containing them.
(FR) La présente invention concerne des constructions pour l'expression d'une protéine chimérique d'enveloppe de virus comprenant une séquence nucléique d'un gène codant pour une protéine fusionnée avec une séquence nucléique codant pour une protéine transmembranaire d'enveloppe de virus, les vecteurs ou particules virales les contenant, les cellules transformées par lesdites particules virales ainsi que les procédés de production desdites particules virales. L'invention comprend également l'utilisation desdites particules virales pour la préparation d'un médicament destiné au traitement et/ou à la prévention de maladie traitable par thérapie génique ainsi que les compositions pharmaceutiques les contenant.
Designated States: CA, JP, US
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: French (FR)
Filing Language: French (FR)