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1. (WO1998049303) COMPOSITIONS AND METHODS FOR CONFERRING TICK IMMUNITY AND PREVENTING TICK BORNE DISEASES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/049303 International Application No.: PCT/US1998/008371
Publication Date: 05.11.1998 International Filing Date: 29.04.1998
Chapter 2 Demand Filed: 27.11.1998
IPC:
A61K 39/00 (2006.01) ,C07K 14/435 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
Applicants:
YALE UNIVERSITY [US/US]; 451 College Street New Haven, CT 06520, US (AT, AU, BE, CA, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, JP, LU, MC, NL, PT, SE)
KANTOR, Fred, S. [US/US]; US (UsOnly)
FIKRIG, Erol [US/US]; US (UsOnly)
NAZARIO, Sylvette [US/US]; US (UsOnly)
DAS, Subrata [IN/US]; US (UsOnly)
Inventors:
KANTOR, Fred, S.; US
FIKRIG, Erol; US
NAZARIO, Sylvette; US
DAS, Subrata; US
Agent:
HALEY, James, F., Jr. ; Fish & Neave 1251 Avenue of the Americas New York, NY 10020, US
VOSSIUS & PARTNER; Siebertstrasse 4 81675 München, DE
Priority Data:
60/043,15429.04.1997US
Title (EN) COMPOSITIONS AND METHODS FOR CONFERRING TICK IMMUNITY AND PREVENTING TICK BORNE DISEASES
(FR) COMPOSITIONS ET PROCEDES D'IMMUNISATION CONTRE LES TIQUES ET DE PREVENTION DES MALADIES VEHICULEES PAR LES TIQUES
Abstract:
(EN) Methods and compositions for conferring tick immunity and preventing or reducing the transmission of tick-borne pathogens. $i(I. scapularis) polypeptides and fragments, fusion and multimeric proteins, DNA molecules encoding them, antibodies directed against the polypeptides, fusion proteins or multimeric proteins. Vaccines comprising $i(I. scapularis) polypeptides alone or in addition to other protective polypeptides. Methods comprising the polypeptides, antibodies and vaccines.
(FR) La présente invention concerne des compositions et procédés d'immunisation contre les tiques et de prévention ou de réduction de la pathogénicité des agents véhiculés par les tiques. L'invention concerne notamment des polypeptides et fragments de $i(I. scapularis), certaines de leurs protéines de fusion et multimères, des molécules d'ADN les codant, des anticorps dirigés contre ces polypeptides, certaines de leurs protéines de fusion ou de leurs protéines multimères. L'invention concerne en outre des vaccins comprenant des polypeptides de $i(I. scapularis) seuls ou an adjonction à d'autres polypeptides protecteurs. L'invention concerne enfin des procédés portant sur ces polypeptides, anticorps et vaccins.
Designated States: AU, CA, JP, US
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1017806JP2001523964 CA2288433AU1998072584