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. (WO1998049295) LIGAND POLYPEPTIDE FOR THE G PROTEIN-COUPLED RECEPTOR FROM HUMAN PITUITARY GLANDS

Pub. No.:    WO/1998/049295    International Application No.:    PCT/JP1998/001923
Publication Date: Fri Nov 06 00:59:59 CET 1998 International Filing Date: Tue Apr 28 01:59:59 CEST 1998
IPC: A61K 38/00
C07K 14/47
C07K 14/72
Applicants: TAKEDA CHEMICAL INDUSTRIES, LTD.
HINUMA, Shuji
FUKUSUMI, Shoji
Inventors: HINUMA, Shuji
FUKUSUMI, Shoji
Title: LIGAND POLYPEPTIDE FOR THE G PROTEIN-COUPLED RECEPTOR FROM HUMAN PITUITARY GLANDS
Abstract:
The present invention relates to the murine-derived ligand polypeptide for the G protein-coupled receptor proteins. The ligand polypeptide or the DNA which codes for the ligand polypeptide can be used for (1) development of medicines such as pituitary function modulators, central nervous system function modulators, and pancreatic function modulators, (2) development of receptor binding assay systems using the expression of recombinant receptor proteins and screening of pharmaceutical candidate compounds, and (3) production of non-human transgenic animals or non-human knockout animals for analyzing a function of the genes.