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1. (WO1998049291) INTRACELLULAR GLUCOCORTICOID-INDUCED LEUCINE ZIPPERS MODULATORS OF APOPTIC CELL DEATH PATHWAYS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/049291 International Application No.: PCT/EP1998/002490
Publication Date: 05.11.1998 International Filing Date: 27.04.1998
Chapter 2 Demand Filed: 12.11.1998
IPC:
A61K 38/00 (2006.01) ,A61K 48/00 (2006.01) ,C07K 14/47 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
Applicants:
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. [NL/NL]; John B. Gorsiraweg 14 Curacao, AN (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
RICCARDI, Carlo [IT/IT]; IT (UsOnly)
Inventors:
RICCARDI, Carlo; IT
Agent:
PIERACCIOLI, Daniele; Istituto Farmacologico Serono S.p.A. Via Casilina, 125 I-00176 Rome, IT
Priority Data:
97107033.928.04.1997EP
Title (EN) INTRACELLULAR GLUCOCORTICOID-INDUCED LEUCINE ZIPPERS MODULATORS OF APOPTIC CELL DEATH PATHWAYS
(FR) GLISSIERES A LEUCINE INDUITES PAR UN GLUCOCORTICOIDE SERVANT DE MODULATEURS INTRACELLULAIRES DES MECANISMES D'APOPTOSE CELLULAIRE
Abstract:
(EN) A DNA sequence encoding a glucocorticoid-induced leucine-zipper family related protein (GILR), isoforms, fragments or analogs thereof, said GILR, isoforms, fragments or analogs thereof capable of inhibiting apoptosis and stimulating lymphocyte activity, GILR proteins, isoforms, analogs, fragments and derivatives thereof encoded by the aforesaid DNA sequence, their preparation and uses.
(FR) L'invention concerne une séquence d'ADN codant pour une protéine (GILR) associée à la famille des glissières à leucine et induite par un glucocorticoïde, pour des isoformes, fragments ou analogues de cette protéine, cette protéine GILR, des isoformes, fragments ou analogues de celle-ci étant capables d'inhiber l'apoptose et de stimuler l'activité des lymphocytes. L'invention concerne également des protéines GILR, des isoformes, analogues, fragments et dérivés de celles-ci, codés par ladite séquence d'ADN, ainsi que la préparation et les utilisations de ceux-ci.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL132632EP0884385EP1007672US6833348US20040194160US20050095681
JP2001523102 CA2287906AU1998077593DK1007672