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1. (WO1998049282) METHOD FOR DETECTING CHANGES IN GENE EXPRESSION CAUSED BY THE TRANSFER OF GENE TO BE TESTED
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/049282 International Application No.: PCT/JP1998/001935
Publication Date: 05.11.1998 International Filing Date: 27.04.1998
Chapter 2 Demand Filed: 26.11.1998
IPC:
C12N 15/10 (2006.01) ,C12Q 1/68 (2006.01)
Applicants: MURAMATSU, Masaaki[JP/JP]; JP (UsOnly)
YANO, Kazuhiro[JP/JP]; JP (UsOnly)
NOGUCHI, Teruhisa[JP/JP]; JP (UsOnly)
SUYAMA, Akira[JP/JP]; JP (UsOnly)
HELIX RESEARCH INSTITUTE[JP/JP]; 1532-3, Yana Kisarazu-shi Chiba 292-0812, JP (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HU, ID, IE, IL, IS, IT, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
Inventors: MURAMATSU, Masaaki; JP
YANO, Kazuhiro; JP
NOGUCHI, Teruhisa; JP
SUYAMA, Akira; JP
Agent: SHIMIZU, Hatsushi ; Kantetsu Tsukuba Building 6F 1-1-1, Oroshi-machi Tsuchiura-shi Ibaraki 300-0847, JP
Priority Data:
9/11163528.04.1997JP
Title (EN) METHOD FOR DETECTING CHANGES IN GENE EXPRESSION CAUSED BY THE TRANSFER OF GENE TO BE TESTED
(FR) PROCEDE SERVANT A DETECTER DES MODIFICATIONS DE L'EXPRESSION GENETIQUE PROVOQUEES PAR LE TRANSFERT DE GENES A CONTROLER
Abstract:
(EN) A method for detecting changes in gene expression in cells caused by the expression of a gene to be tested by extracting mRNAs from cells into which the gene to be tested has been transferred and expressed and control cells into which the gene to be tested has not been transferred and comparing these mRNAs in constitution. This method also makes it possible to screen genes suffering from changes in the expression thereof in cells due to the expression of the gene to be tested in the cells.
(FR) Procédé servant à détecter des modifications de l'expression génétique dans des cellules, qui sont provoquées par l'expression d'un gène à contrôler, ce qui consiste à extraire des ARNm depuis des cellules dans lesquelles le gène à contrôler a été transféré et exprimé, ainsi que depuis des cellules de contrôle dans lesquelles le gène à contrôler n'a pas été transféré, puis à comparer les constitutions respectives de ces ARNm. Ce procédé permet également de cribler des gènes dont l'expression a subi des modifications dans des cellules sous l'effet de l'expression du gène à contrôler dans ces cellules.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)