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1. (WO1998049196) CALCITONIN RECEPTOR-BINDING PEPTIDES

Pub. No.:    WO/1998/049196    International Application No.:    PCT/US1998/008864
Publication Date: Fri Nov 06 00:59:59 CET 1998 International Filing Date: Sat May 02 01:59:59 CEST 1998
IPC: A61K 38/00
C07K 14/585
Applicants: DIATIDE, INC.
Inventors: DEAN, Richard, T.
BUSH, Larry, R.
PEARSON, Daniel, A.
LISTER-JAMES, John
Title: CALCITONIN RECEPTOR-BINDING PEPTIDES
Abstract:
This invention relates to calcitonin receptor binding reagents comprising compounds which are covalently linked to a radiometal chelator. The invention is embodied as calcitonin receptor binding peptide derivatives and analogues of calcitonin which may be radiolabeled with a suitable isotope and used as radiodiagnostic or radiotherapeutic agents. Methods and kits for making, radiolabeling and using such reagents diagnostically and therapeutically in a mammalian body are also provided.