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1. (WO1998049174) SYNTHESIS OF PLATINUM COMPLEXES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/049174    International Application No.:    PCT/CN1998/000069
Publication Date: 05.11.1998 International Filing Date: 30.04.1998
Chapter 2 Demand Filed:    03.11.1998    
IPC:
C07F 15/00 (2006.01)
Applicants: THE CHINESE UNIVERSITY OF HONG KONG [CN/CN]; Shatin, New Territories, Hong Kong Special Administrative Region (CN)
Inventors: AU-YEUNG, Steve, C., F.; (CN).
HO, Yee, Ping; (CN).
LIN, Ge; (CN).
HAN, Xiuwen; (CN).
WANG, Xinning; (CN).
LU, Shiwei; (CN).
JIANG, Tao; (CN)
Agent: NTD PATENT & TRADEMARK AGENCY LTD BEIJING OFFICE; 10/F., 6 Beisanhuanzhonglu Road, Dewai, Beijing 100011 (CN)
Priority Data:
97102796.X 30.04.1997 CN
Title (EN) SYNTHESIS OF PLATINUM COMPLEXES AND USES THEREOF
(FR) SYNTHESE DE COMPLEXES DE PLATINE ET SES UTILISATIONS
Abstract: front page image
(EN)This invention provides novel antitumor demethylcantharidin platinum complexes. This invention also provides a composition comprising at least one of said demethylcantharidin platinum complexes and a suitable carrier. This invention provides a pharmaceutical composition comprising effective amount of at least one of the said demethylcantharidin platinum complexes and a pharmaceutically acceptable carrier. This invention provides a method of inhibiting the growth of tumorous cells comprising contacting the cells with an amount of said demethylcantharidin platinum complex effective to inhibit the growth of said tumorous cells. This invention provides a method of inhibiting the growth of tumorous cells in a subject comprising administering to the subject with an amount of the said demethylcantharidin platinum complexes effective to inhibit the growth of said tumorous cells in the subject. Finally, this invention provides methods for producing said demethylcantharidin platinum complexes.
(FR)L'invention concerne de nouveaux complexes antitumoraux de déméthylcanthadirine platine. Cette invention concerne également une composition comprenant au moins un desdits complexes de déméthylcantharidine platine et un support convenable. Cette invention concerne en outre une composition pharmaceutique comprenant une dose suffisante d'au moins un desdits complexes de déméthylcanthadirine platine et un excipient pharmaceutiquement acceptable. Cette invention porte sur un procédé d'inhibition de la croissance de cellules tumorales consistant à mettre les cellules en contact avec une dose dudit complexe de déméthylcanthridine platine permettant d'inhiber la croissance desdites cellules tumorales. Cette invention concerne un procédé d'inhibition de la croissance des cellules tumorales chez un sujet, consistant à administrer au sujet une dose desdits complexes de déméthylcantharidine platine apte à inhiber la croissance desdites cellules tumorales chez le sujet. Enfin, cette invention concerne des procédés de production desdits complexes de déméthylcantharidine platine.
Designated States: AT, AU, BR, CA, CN, FI, IL, JP, KP, KR, LU, MX, NO, NZ, PL, PT, RO, RU, SE, SG.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)