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1. (WO1998049170) SPIRO-AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/049170    International Application No.:    PCT/GB1998/001179
Publication Date: 05.11.1998 International Filing Date: 22.04.1998
Chapter 2 Demand Filed:    21.09.1998    
IPC:
C07D 491/10 (2006.01)
Applicants: MERCK SHARP & DOHME LIMITED [GB/GB]; Hertford Road, Hoddesdon, Hertfordshire, EN11 9BU (GB) (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW only).
CURTIS, Neil, Roy [GB/GB]; (GB) (For US Only).
ELLIOTT, Jason, Matthew [GB/GB]; (GB) (For US Only).
HOLLINGWORTH, Gregory, John [GB/GB]; (GB) (For US Only).
JACKSON, Philips, Stephen [GB/GB]; (GB) (For US Only).
KULAGOWSKI, Janusz, Jozef [GB/GB]; (GB) (For US Only).
SEWARD, Eileen, Mary [IE/GB]; (GB) (For US Only).
SWAIN, Christopher, John [GB/GB]; (GB) (For US Only).
WILLIAMS, Brian, John [GB/GB]; (GB) (For US Only)
Inventors: CURTIS, Neil, Roy; (GB).
ELLIOTT, Jason, Matthew; (GB).
HOLLINGWORTH, Gregory, John; (GB).
JACKSON, Philips, Stephen; (GB).
KULAGOWSKI, Janusz, Jozef; (GB).
SEWARD, Eileen, Mary; (GB).
SWAIN, Christopher, John; (GB).
WILLIAMS, Brian, John; (GB)
Agent: HISCOCK, Ian; Merck & Co., Inc., European Patent Dept., Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR (GB)
Priority Data:
9708484.2 25.04.1997 GB
Title (EN) SPIRO-AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
(FR) DERIVES SPIRO-AZACYCLIQUES ET LEUR UTILISATION COMME AGENTS THERAPEUTIQUES
Abstract: front page image
(EN)Substituted spiro-azacyclic derivatives of structural formula (I) are tachykinin receptor antagonists of use, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
(FR)L'invention concerne des dérivés spiro-azacyliques substitués de la formule développée (I) constituant des antagonistes de récepteur de tachykinine s'utilisant, par exemple, dans le traitement ou la prévention de douleurs, d'inflammations, de migraines, de vomissements et d'algies post-zostériennes.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)