Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1998049131) NEW BENZYLAMINE AND PHENYLETHYLAMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/049131 International Application No.: PCT/EP1998/002530
Publication Date: 05.11.1998 International Filing Date: 29.04.1998
Chapter 2 Demand Filed: 26.11.1998
IPC:
C07C 217/58 (2006.01) ,C07C 217/60 (2006.01) ,C07C 271/16 (2006.01) ,C07C 317/22 (2006.01) ,C07C 323/20 (2006.01) ,C07D 295/192 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
217
Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
54
having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
56
with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
58
with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
217
Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
54
having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
56
with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
60
linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
271
Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups
06
Esters of carbamic acids
08
having oxygen atoms of carbamate groups bound to acyclic carbon atoms
10
with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
16
to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
317
Sulfones; Sulfoxides
16
having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
22
with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
323
Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
10
containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
18
having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
20
with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
295
Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
16
acylated on ring nitrogen atoms
18
by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
182
Radicals derived from carboxylic acids
192
from aromatic carboxylic acids
Applicants:
BOEHRINGER INGELHEIM PHARMA KG [DE/DE]; Postfach 200 D-55216 Ingelheim am Rhein, DE (AT, AU, BE, BG, BR, BY, CA, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, ID, IE, IL, IT, JP, KR, KZ, LT, LU, LV, MC, MX, NL, NO, NZ, PL, PT, RO, RU, SE, SG, SI, SK, TR, UA, UZ, VN, YU)
ANDERSKEWITZ, Ralf [DE/DE]; DE (UsOnly)
SCHROMM, Kurt [DE/DE]; DE (UsOnly)
RENTH, Ernst-Otto [DE/DE]; DE (UsOnly)
BIRKE, Franz [DE/DE]; DE (UsOnly)
JENNEWEIN, Hans, Michael [DE/DE]; DE (UsOnly)
MEADE, Christopher, John, Montague [GB/DE]; DE (UsOnly)
Inventors:
ANDERSKEWITZ, Ralf; DE
SCHROMM, Kurt; DE
RENTH, Ernst-Otto; DE
BIRKE, Franz; DE
JENNEWEIN, Hans, Michael; DE
MEADE, Christopher, John, Montague; DE
Priority Data:
197 18 334.430.04.1997DE
Title (DE) NEUE BENZYLAMINDERIVATE UND PHENYLETHYLAMINDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL
(EN) NEW BENZYLAMINE AND PHENYLETHYLAMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS
(FR) NOUVEAUX DERIVES DE BENZYLAMINE ET DE PHENYLETHYLAMINE, LEURS PROCEDES DE PREPARATION ET LEUR UTILISATION COMME MEDICAMENTS
Abstract:
(DE) Die vorliegende Erdindung betrifft neue Phenylaminderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel insbesondere als LTB4-Rezeptor Antagonisten. Die erfindungsgemäßen Phenylamine entsprechen der allgemeinen Formel (I).
(EN) New phenylamine derivatives, processes for preparing the same and their use as medicaments are disclosed. These phenylamines have the general formula (I).
(FR) L'invention concerne de nouveaux dérivés de phénylamine, leurs procédés de préparation et leur utilisation comme médicaments. Les phénylamines décrites répondent à la formule générale (I).
front page image
Designated States: AU, BG, BR, BY, CA, CN, CZ, EE, HU, ID, IL, JP, KR, KZ, LT, LV, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TR, UA, US, UZ, VN, YU
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
MXPA/a/1999/009960CO4950516AR011469EP0980351US6288277JP2001524966
CA2287991PT980351AU1998077600DK0980351