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1. (WO1998048873) DEVICE FOR ADMINISTERING INSULIN IN CONTROLLED DOSAGES BY CONTROLLING TOTAL INHALED VOLUME
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/048873 International Application No.: PCT/US1998/008238
Publication Date: 05.11.1998 International Filing Date: 23.04.1998
Chapter 2 Demand Filed: 12.11.1998
IPC:
A61M 15/00 (2006.01) ,A61M 16/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15
Inhalators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
16
Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
Applicants:
ARADIGM CORPORATION [US/US]; 26219 Eden Landing Road Hayward, CA 94545, US
Inventors:
GONDA, Igor; US
RUBSAMEN, Reid, M.; US
FARR, Stephen, J.; US
Agent:
BOZICEVIC, Karl; Bozicevic, Field & Francis LLP Suite 200 285 Hamilton Avenue Palo Alto, CA 94301, US
Priority Data:
08/846,24325.04.1997US
Title (EN) DEVICE FOR ADMINISTERING INSULIN IN CONTROLLED DOSAGES BY CONTROLLING TOTAL INHALED VOLUME
(FR) DISPOSITIF D'ADMINISTRATION DE DOSES REGULEES D'INSULINE PAR MAITRISE DU VOLUME INHALE TOTAL
Abstract:
(EN) Dosages of inhaled insulin are controlled within a narrow range by controlling the total volume of air inhaled by a patient. By repeatedly delivering aerosolized insulin with the same total inhaled volume of air, the amount of insulin delivered to the patient each time is consistent. A device (40) comprises a means (11, 29) for measuring inhaled volume and for halting inhalation at a predetermined point. The device also comprises an adjustable means (9) for applying various amounts of force to a container (1) of formulation (5) to expel different amounts of drugs from the container based on the force applied.
(FR) On agit sur le dosage d'insuline inhalée avec une marge étroite en maîtrisant le volume total d'air qu'inhale un patient. En administrant de manière répétitive de l'insuline en aérosol avec le même volume total d'air inhalé, la quantité d'insuline administrée chaque fois au patient est constante. Le dispositif (40) de l'invention comprend un mécanisme (11, 29) permettant de mesurer le volume inhalé et de faire cesser l'inhalation à un moment prédéterminé. Il comprend également un mécanisme réglable (9) permettant d'exercer des forces différentes sur un récipient (1) contenant la formulation (5) et ce, pour faire sortir du récipient des quantités de médicament variant selon la force exercée.
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Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1011767EP1576978JP2002504833 AU1998072556