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1. (WO1998048835) ANTI-HELICOBACTER VACCINE COMPOSITION FOR USE BY THE SUBDIAPHRAGMATIC SYSTEMIC ROUTE, AND COMBINED MUCOSAL/PARENTERAL IMMUNIZATION METHOD

Pub. No.:    WO/1998/048835    International Application No.:    PCT/US1998/008890
Publication Date: Fri Nov 06 00:59:59 CET 1998 International Filing Date: Fri May 01 01:59:59 CEST 1998
IPC: A61K 48/00
Applicants: MERIEUX ORAVAX
GUY, Bruno
HAENSLER, Jean
LEE, Cynthia, K.
WELTZIN, Richard, A.
MONATH, Thomas, P.
Inventors: GUY, Bruno
HAENSLER, Jean
LEE, Cynthia, K.
WELTZIN, Richard, A.
MONATH, Thomas, P.
Title: ANTI-HELICOBACTER VACCINE COMPOSITION FOR USE BY THE SUBDIAPHRAGMATIC SYSTEMIC ROUTE, AND COMBINED MUCOSAL/PARENTERAL IMMUNIZATION METHOD
Abstract:
The subject of the invention is the use of an immunogenic agent derived from Helicobacter, in the manufacture of a pharmaceutical composition intended for the induction of a T helper 1 (Th1) type immune response against Helicobacter, to prevent or treat a Helicobacter infection in a mammal. This is in particular achieved when the pharmaceutical composition is intended to be administered by the systemic or parenteral route, for example, in the part of the mammal situated under its diaphragm. Also included in the invention is a mucosal/parenteral immunization method for the prevention or treatment of Helicobacter infection.