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Machine translation
1. (WO1998048830) METHOD FOR PROMOTING MYOGENESIS USING OSTEOGENIC PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/048830    International Application No.:    PCT/US1998/008466
Publication Date: 05.11.1998 International Filing Date: 27.04.1998
Chapter 2 Demand Filed:    24.11.1998    
IPC:
A61K 38/18 (2006.01), C12N 5/077 (2010.01), A61K 38/00 (2006.01), A61K 48/00 (2006.01)
Applicants: TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; Suite 300, 3700 Market Street, Philadelphia, PA 19104 (US) (AT, AU, BE, CA, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, JP, LU, MC, NL, PT, SE only).
EMERSON, Charles, P. [US/US]; (US) (For US Only).
BORYCKI, Anne-Gaelle [US/US]; (US) (For US Only).
BRUNK, Brian [US/US]; (US) (For US Only)
Inventors: EMERSON, Charles, P.; (US).
BORYCKI, Anne-Gaelle; (US).
BRUNK, Brian; (US)
Agent: REED, Janet, E.; Dann, Dorfman, Herrell and Skillman, Suite 720, 1601 Market Street, Philadelphia, PA 19103-2307 (US)
Priority Data:
60/045,012 28.04.1997 US
60/058,225 09.09.1997 US
Title (EN) METHOD FOR PROMOTING MYOGENESIS USING OSTEOGENIC PROTEINS
(FR) PROCEDES DESTINES A FAVORISER LA MYOGENESE EN UTILISANT UNE PROTEINE OSTEOGENIQUE
Abstract: front page image
(EN)Methods and compositions are provided for stimulating lineage commitment of adult or embryonic myogenic stem cells. The methods comprise treating the cells with the osteogenic protein, OP-1, at a concentration effective to induce myogenesis of stem cells. The methods are useful for therapeutic purposes in embryonic development and in repair/regeneration of mature muscle.
(FR)L'invention concerne des procédés et des compositions destinés à stimuler l'obligation de lignage de cellules myogènes souches adultes ou embryonnaires. Ces procédés consistent à traiter les cellules avec la protéine ostéogénique, OP-1, à une concentration suffisante pour induire la myogenèse des cellules souches. Ces procédés ont des fins thérapeutiques pour le développement embryonnaire et pour la réparation/régénération d'un muscle mature.
Designated States: AU, CA, JP, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)