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1. (WO1998048809) USE OF IMMUNOMODULATING AGENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/048809 International Application No.: PCT/NO1998/000134
Publication Date: 05.11.1998 International Filing Date: 29.04.1998
Chapter 2 Demand Filed: 06.11.1998
IPC:
A61K 38/00 (2006.01) ,A61K 38/17 (2006.01) ,C12N 9/12 (2006.01) ,C12N 15/11 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
12
transferring phosphorus containing groups, e.g. kinases (2.7)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
Applicants:
LAURAS AS [NO/NO]; c/o Forskningsparken AS Gaustadalléen 21 N-0349 Oslo, NO (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
TASKÉN, Kjetil [NO/NO]; NO (UsOnly)
AANDAHL, Einar, Martin [NO/NO]; NO (UsOnly)
AUKRUST, Pål [NO/NO]; NO (UsOnly)
SKÅLHEGG, Bjørn, S. [NO/NO]; NO (UsOnly)
MÜLLER, Fredrik [NO/NO]; NO (UsOnly)
FRØLAND, Stig [NO/NO]; NO (UsOnly)
HANSSON, Vidar [NO/NO]; NO (UsOnly)
Inventors:
TASKÉN, Kjetil; NO
AANDAHL, Einar, Martin; NO
AUKRUST, Pål; NO
SKÅLHEGG, Bjørn, S.; NO
MÜLLER, Fredrik; NO
FRØLAND, Stig; NO
HANSSON, Vidar; NO
Agent:
ONSAGERS PATENTKONTOR-DEFENSOR AS; P.O. Box 265 Sentrum N-0103 Oslo, NO
Priority Data:
97199729.04.1997NO
Title (EN) USE OF IMMUNOMODULATING AGENTS
(FR) UTILISATION D'AGENTS IMMUNOMODULATEURS
Abstract:
(EN) It is described the use of several compounds capable of inhibiting cAMP-dependent protein kinase A (PKA) to produce a medicament increasing the T-cell proliferation in patients with immunosuppressive diseases. Inhibitors include cAMP analogues, ribozymes, antisense DNA and peptides binding to the anchoring region of PKA.
(FR) L'invention concerne l'utilisation de plusieurs composés capables d'inhiber la protéine kinase A (PKA) AMPc-dépendante afin de produire un médicament qui favorise la prolifération des lymphocytes T chez des patients atteints d'une maladie immunosuppressive. Parmi ces inhibiteurs, on trouve des analogues de l'AMPc, des ribozymes, de l'ADN antisens et des peptides se fixant sur la zone d'ancrage de la PKA.
front page image
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO19995269ES2171018EP1024809JP2010111688US20050250727US7192932
JP2002501499 CA2288215DE000069804125PT1024809NZ501181AU1998070865
DK1024809