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1. (WO1998048783) MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS AND FOR DELIVERY OF DRUGS INTO THE BLOODSTREAM
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/048783 International Application No.: PCT/US1998/008827
Publication Date: 05.11.1998 International Filing Date: 30.04.1998
Chapter 2 Demand Filed: 03.11.1998
IPC:
A61K 41/00 (2006.01) ,A61K 47/48 (2006.01) ,A61K 49/22 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41
Medicinal preparations obtained by treating materials with wave energy or particle radiation
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
22
Echographic preparations; Ultrasound imaging preparations
Applicants:
POINT BIOMEDICAL CORPORATION [US/US]; 887A Industrial Road San Carlos, CA 94070, US
Inventors:
OTTOBONI, Thomas, B.; US
SHORT, Robert, E.; US
YAMAMOTO, Ronald, K.; US
Agent:
SUYAT, Reginald, J.; Fish & Richardson P.C. Suite 100 2200 Sand Hill Road Menlo Park, CA 94025, US
Priority Data:
08/847,15330.04.1997US
Title (EN) MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS AND FOR DELIVERY OF DRUGS INTO THE BLOODSTREAM
(FR) MICROPARTICULES UTILISABLES COMME AGENTS DE CONTRASTE OU POUR LA LIBERATION DE MEDICAMENTS DANS LE FLUX SANGUIN
Abstract:
(EN) Microparticles are provided comprising a shell of an outer layer of a biologically compatible material and an inner layer of biodegradable polymer. The core of the microparticles contain a gas, liquid or solid for use in drug delivery or as a contrast agent for ultrasonic contrast imaging. The microparticles are capable of passing through the capillary systems of a subject.
(FR) L'invention porte sur des microparticules comportant une enveloppe faite d'une couche extérieure d'un matériau biocompatible, une couche intérieure d'un matériau biodégradable, ainsi qu'un noyau gazeux, liquide ou solide, et qui servent à l'administration de médicaments ou d'agents de contraste pour l'imagerie par ultrasons. Lesdites microparticules peuvent circuler dans les systèmes capillaires d'un patient.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)