Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1998048616) ANIMALS CARRYING 25-HYDROXYLATED VITAMIN D¿3?24-HYDROXYLASE GENE TRANSFERRED THEREINTO
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/048616 International Application No.: PCT/JP1998/001922
Publication Date: 05.11.1998 International Filing Date: 27.04.1998
Chapter 2 Demand Filed: 13.11.1998
IPC:
C12N 9/02 (2006.01) ,C12N 15/85 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
02
Oxidoreductases (1.), e.g. luciferase
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
Applicants:
TAKEDA CHEMICAL INDUSTRIES, LTD. [JP/JP]; 1-1, Doshomachi 4-chome Chuo-ku Osaka-shi Osaka 541-0045, JP (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HU, ID, IE, IL, IS, IT, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
KASUGA, Hisao [JP/JP]; JP (UsOnly)
ISAKA, Masami [JP/JP]; JP (UsOnly)
MATSUOKA, Kunio [JP/JP]; JP (UsOnly)
Inventors:
KASUGA, Hisao; JP
ISAKA, Masami; JP
MATSUOKA, Kunio; JP
Agent:
ASAHINA, Tadao ; Osaka Plant of Takeda Chemical Industries, Ltd. 17-85, Jusohonmachi 2-chome Yodogawa-ku Osaka-shi Osaka 532-0024, JP
Priority Data:
9/11250230.04.1997JP
Title (EN) ANIMALS CARRYING 25-HYDROXYLATED VITAMIN D324-HYDROXYLASE GENE TRANSFERRED THEREINTO
(FR) ANIMAUX PORTEURS D'UN GENE TRANSFERE DE 25-HYDROXYVITAMINE D3-24-HYDROXYLASE
Abstract:
(EN) Transgenic non-human mammals which are usable as pathological animal models of kidney diseases, bone diseases, joint diseases, lung diseases, hyperlipemia, arteriosclerosis, heart diseases, diabetes, obesity, diagnostic diseases, infections, allergic diseases, endocrine diseases, dementia, cancer or complications of these diseases and enable the clarification of the pathologic mechanisms of these diseases, examination on the therapeutics therefore and screening of remedies therefore.
(FR) Mammifères transgéniques pouvant être utilisés comme modèles pathologiques animaux pour les maladies des reins, des os, des articulations, des poumons, l'hyperlipémie, l'artériosclérose, les maladies cardiaques, le diabète, l'obésité, les maladies digestives, les infections, les maladies allergiques, endocrines, la démence, le cancer ou des complications de ces maladies. Ces animaux permettent en outre d'éclaircir les mécanismes pathologiques de ces maladies, d'étudier les traitements pour ces dernières et de sélectionner des médicaments pour ces maladies.
front page image
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, GW, HU, ID, IL, IS, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, UA, US, UZ, VN, YU
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
EP0992189US6316689CA2287979AU1998070816