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1. WO1998047492 - NANOSIZED ASPARTYL PROTEASE INHIBITORS

Publication Number WO/1998/047492
Publication Date 29.10.1998
International Application No. PCT/US1998/007845
International Filing Date 14.04.1998
Chapter 2 Demand Filed 10.11.1998
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
A61K 9/14 (2006.01)
CPC
A61K 9/146
Applicants
  • VERTEX PHARMACEUTICALS INCORPORATED [US/US]; 130 Waverly Street Cambridge, MA 02139-4242, US (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
  • CHATURVEDI, Pravin, Ramsewak [IN/US]; US (UsOnly)
  • TUNG, Roger, Dennis [US/US]; US (UsOnly)
  • BOGER, Joshua, S. [US/US]; US (UsOnly)
Inventors
  • CHATURVEDI, Pravin, Ramsewak; US
  • TUNG, Roger, Dennis; US
  • BOGER, Joshua, S.; US
Agents
  • HALEY, James, F., Jr.; Fish & Neave 1251 Avenue of the Americas New York, NY 10020 , US
  • VOSSIUS & PARTNER; Siebertstrasse 4 D-81675 München, DE
Priority Data
08/844,01518.04.1997US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NANOSIZED ASPARTYL PROTEASE INHIBITORS
(FR) INHIBITEURS D'ASPARTYLE PROTEASE NANOMETRIQUES
Abstract
(EN)
The present invention relates to particles of the free base form of aspartyl protease inhibitors and pharmaceutical dosage forms containing those particles. The invention also relates to methods of treating mammals with those pharmaceutical dosage forms.
(FR)
La présente invention concerne des particules d'inhibiteurs de la forme base libre de l'aspartyle protéase et des présentations pharmaceutiques contenant lesdites particules. L'invention se rapporte également à des procédés permettant de traiter des mammifères à l'aide de ces présentations pharmaceutiques.
Also published as
Latest bibliographic data on file with the International Bureau