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1. WO1998034667 - GENE THERAPEUTIC TREATMENT OF BLOOD VESSEL ASSOCIATED DISORDERS

Publication Number WO/1998/034667
Publication Date 13.08.1998
International Application No. PCT/EP1998/000723
International Filing Date 09.02.1998
Chapter 2 Demand Filed 12.08.1998
IPC
A61K 38/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
44Oxidoreductases (1)
A61K 47/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
CPC
A61K 38/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
44Oxidoreductases (1)
A61K 47/6957
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
6957the form being a device or a kit, e.g. stents or microdevices
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61M 2025/105
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
25Catheters; Hollow probes
10Balloon catheters
1043with special features or adapted for special applications
105having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
C12Y 114/13039
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
YENZYMES
114Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
13with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
13039Nitric-oxide synthase (NADPH dependent) (1.14.13.39)
Applicants
  • LEUVEN RESEARCH & DEVELOPMENT VZW GROOT BEGIJNHOF [BE]/[BE] (UsOnly)
  • VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE [BE]/[BE] (UsOnly)
  • VARENNE, Olivier, Henry [BE]/[BE] (UsOnly)
  • COLLEN, Désiré, José [BE]/[BE] (UsOnly)
  • JANSSENS, Stefan, Pierre [BE]/[BE] (UsOnly)
Inventors
  • VARENNE, Olivier, Henry
  • COLLEN, Désiré, José
  • JANSSENS, Stefan, Pierre
Agents
  • VAN SOMEREN, Petronella, Francisca, Hendrika, Maria
Priority Data
97200330.507.02.1997EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GENE THERAPEUTIC TREATMENT OF BLOOD VESSEL ASSOCIATED DISORDERS
(FR) TRAITEMENT PAR THERAPIE GENIQUE DES TROUBLES ASSOCIES AUX VAISSEAUX SANGUINS
Abstract
(EN)
The invention relates to a catheter containing an inflatable balloon, which is at its perifery provided with hollow extensions that communicate between the outside of the balloon and the lumen of the catheter for use in the gene therapeutic treatment of local disorders by transfer of a desired gene to a target cell or tissue being part of or being located in the vicinity of a blood vessel. The catheter is preferably the Infiltrator$m(3) catheter.
(FR)
Cette invention concerne un cathéter contenant un ballonnet gonflable qui est pourvu sur sa périphérie de prolongements creux qui communiquent entre l'extérieur du ballonnet et la lumière du cathéter. On utilise ce cathéter dans le traitement par thérapie génique de troubles localisés, qui consiste à envoyer un gène désiré jusqu'à une cellule ou un tissu cible qui fait partie d'un vaisseau sanguin ou qui se situe au voisinage de ce dernier. Le cathéter est de préférence un cathéter Infiltrator$m(3).
Also published as
Latest bibliographic data on file with the International Bureau