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1. WO1998034118 - DIAGNOSTIC METHODS AND COMPOSITIONS BASED ON THE DISTRIBUTION OF RAD51

Publication Number WO/1998/034118
Publication Date 06.08.1998
International Application No. PCT/US1998/001825
International Filing Date 30.01.1998
Chapter 2 Demand Filed 20.08.1998
IPC
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N 33/574 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
CPC
G01N 33/5011
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
5005involving human or animal cells
5008for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
5011for testing antineoplastic activity
G01N 33/574
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
G01N 33/57415
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
57407Specifically defined cancers
57415of breast
G01N 33/5743
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
57407Specifically defined cancers
5743of skin, e.g. melanoma
Applicants
  • YALE UNIVERSITY [US]/[US]
Inventors
  • HAFF, Thomas
  • RADDING, Charles, M.
  • REDDY, Gurucharan
  • WARD, David, C.
  • GOLUB, Efim, I.
Agents
  • TRECARTIN, Richard, F.
Priority Data
09/007,02014.01.1998US
60/035,83430.01.1997US
60/045,66806.05.1997US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DIAGNOSTIC METHODS AND COMPOSITIONS BASED ON THE DISTRIBUTION OF RAD51
(FR) METHODES DIAGNOSTIQUES ET COMPOSITIONS BASEES SUR LA REPARTITION DE RAD51
Abstract
(EN)
Method of diagnosing individual at risk for a disease comprising determining the distribution of RAD51 foci in a tissue type of a first individual; and comparing said distribution of RAD51 foci form a second normal tissue type from said first individual or a second unaffected individual.
(FR)
L'invention concerne une méthode qui permet de diagnostiquer une maladie chez des individus à risque et qui consiste à déterminer la répartition de foyers de RAD51 dans le type de tissu d'un premier individu, puis à comparer cette répartition avec un second type de tissu normal provenant du premier individu ou d'un second individu ne souffrant pas de ladite maladie.
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