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Machine translation
1. (WO1998032869) EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/032869    International Application No.:    PCT/DK1998/000037
Publication Date: 30.07.1998 International Filing Date: 29.01.1998
Chapter 2 Demand Filed:    19.08.1998    
IPC:
A61K 48/00 (2006.01), C12N 15/867 (2006.01)
Applicants: NEUROSEARCH A/S [DK/DK]; 26B Smedeland, DK-2600 Glostrup (DK) (For US Only).
BAVARIAN NORDIC RESEARCH INSTITUTE A/S [DK/DK]; Naverland 2, 5. th., DK-2600 Glostrup (DK) (For US Only).
JOHANSEN, Teit, E. [DK/DK]; (DK) (For US Only)
Inventors: JOHANSEN, Teit, E.; (DK)
Agent: NEUROSEARCH A/S; 26B Smedeland, DK-2600 Glostrup (DK)
Common
Representative:
NEUROSEARCH A/S; 26B Smedeland, DK-2600 Glostrup (DK)
Priority Data:
0102/97 29.01.1997 DK
Title (EN) EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES
(FR) VECTEURS D'EXPRESSION ET PROCEDES D'EXPRESSION $i(IN VIVO) DE POLYPEPTIDES THERAPEUTIQUES
Abstract: front page image
(EN)The present invention relates to recombinant expression vectors carrying a gene encoding a therapeutically active polypeptide, which gene is under transcriptional control of a ubiquitin promoter. The invention also relates to the use of a ubiquitin promoter to direct $i(in vivo) expression of therapeutic genes after transfer of such genes to the central nervous system.
(FR)L'invention concerne des vecteurs d'expression de recombinaison portant un gène codant un polypeptide actif sur le plan thérapeutique, ledit gène étant placé sous la commande de transcription d'un promoteur d'ubiquitine. Elle concerne également l'utilisation d'un promoteur d'ubiquitine afin de diriger l'expression $i(in vivo) de gènes thérapeutiques après le transfert de ces gènes vers le système nerveux central.
Designated States: JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)