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1. (WO1998032751) PROCESS FOR THE PRODUCTION OF SEMI SYNTHETIC STATINS VIA NOVEL INTERMEDIATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/032751    International Application No.:    PCT/EP1998/000519
Publication Date: 30.07.1998 International Filing Date: 27.01.1998
Chapter 2 Demand Filed:    19.08.1998    
IPC:
C07D 309/30 (2006.01), C07F 5/02 (2006.01), C07F 9/6574 (2006.01)
Applicants: PLUS CHEMICALS B.v. [NL/NL]; Industrieweg 23, NL-3841 RK Mijdrecht (NL) (For All Designated States Except US).
VRIES, Ton, René [NL/NL]; (NL) (For US Only).
WIJNBERG, Hans [NL/NL]; (NL) (For US Only).
FABER, Wijnand, Sjourd [NL/NL]; (NL) (For US Only).
KALKMAN-AGAYN, Venetka, Ivanova [NL/NL]; (NL) (For US Only).
SIBEYN, Mieke [NL/NL]; (NL) (For US Only)
Inventors: VRIES, Ton, René; (NL).
WIJNBERG, Hans; (NL).
FABER, Wijnand, Sjourd; (NL).
KALKMAN-AGAYN, Venetka, Ivanova; (NL).
SIBEYN, Mieke; (NL)
Priority Data:
97200223.2 28.01.1997 EP
97306809.1 03.09.1997 EP
Title (EN) PROCESS FOR THE PRODUCTION OF SEMI SYNTHETIC STATINS VIA NOVEL INTERMEDIATES
(FR) PROCEDE DE PRODUCTION DE STATINES SEMI-SYNTHETIQUES AU MOYEN DE NOUVEAUX INTERMEDIAIRES
Abstract: front page image
(EN)A process has been provided to produce semi synthetic statins, as for instance simvastatin with a high yield, from another statin, preferably a naturally occurring statin, as for instance lovastatin. Also a number of novel intermediate compounds, prepared during said process, has been provided.
(FR)L'invention concerne un procédé de production à fort rendement de statines semi-synthétiques, comme par exemple la simvastatine, à partir d'une autre statine, de préférence une statine naturelle, comme par exemple la lovastatine. L'invention concerne également un certain nombre de nouveaux composés intermédiaires, préparés au cours de ce procédé.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)