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Machine translation
1. (WO1998032333) IMPROVED CHONDROGENIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/032333    International Application No.:    PCT/US1997/022022
Publication Date: 30.07.1998 International Filing Date: 05.12.1997
Chapter 2 Demand Filed:    17.06.1998    
IPC:
C12N 5/077 (2010.01), A61K 38/00 (2006.01)
Applicants: OSIRIS THERAPEUTICS, INC. [US/US]; 2001 Aliceanna Street, Baltimore, MD 21231-2001 (US) (For All Designated States Except US).
PITTENGER, Mark, F. [US/US]; (US) (For US Only).
MACKAY, Alastair, M. [US/US]; (US) (For US Only).
MURPHY, J., Mary [IE/US]; (US) (For US Only).
BARRY, Francis, P. [IE/US]; (US) (For US Only)
Inventors: PITTENGER, Mark, F.; (US).
MACKAY, Alastair, M.; (US).
MURPHY, J., Mary; (US).
BARRY, Francis, P.; (US)
Agent: HERRON, Charles, J.; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein, 6 Becker Farm Road, Roseland, NJ 07068 (US).
SEMIONOW, Raina; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein, 6 Becker Farm Road, Roseland, NJ 07068 (US)
Priority Data:
60/035,274 06.12.1996 US
Title (EN) IMPROVED CHONDROGENIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS
(FR) PERFECTIONNEMENT CONCERNANT LA DIFFERENTIATION CHONDROGENE DE CELLULES SOUCHES DU MESENCHYME HUMAIN
Abstract: front page image
(EN)Disclosed are a composition of chemically defined components having elevated levels of simple sugars which support the enhanced $i(in vitro) chondrogenesis of mesenchymal progenitor cells, a method for $i(in vitro) chondrogenic induction of such progenitor cells and a method of forming human chondrocytes $i(in vitro) from such progenitor cells.
(FR)La présente invention concerne une composition de composants chimiquement définis caractérisés par des niveaux élevés en sucres simples et permettant d'améliorer la chondrogénèse $i(in vitro) des cellules progénitrices du mésenchyme. L'invention concerne également un procédé d'induction $i(in vitro) de la chondrogénèse de telles cellules progénitrices et un procédé de formation $i(in vitro) de chondrocytes humains.
Designated States: AU, CA, JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)