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Machine translation
1. (WO1998031399) LABELLED FACTOR XIIIa SUBSTRATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/031399    International Application No.:    PCT/GB1998/000157
Publication Date: 23.07.1998 International Filing Date: 19.01.1998
Chapter 2 Demand Filed:    08.08.1998    
IPC:
A61K 51/04 (2006.01)
Applicants: NYCOMED AMERSHAM PLC [GB/GB]; Amersham Place, Little Chalfont, Buckinghamshire HP7 9NA (GB) (For All Designated States Except US).
FORSTER, Alan, Michael [GB/GB]; (GB) (For US Only).
KNOX, Peter [GB/GB]; (GB) (For US Only).
MENDIZABAL, Marivi [ES/GB]; (GB) (For US Only).
RICHARDSON, Timothy, Charles [GB/GB]; (GB) (For US Only).
STOREY, Anthony, Eamon [GB/GB]; (GB) (For US Only).
WILSON, Ian, Andrew [GB/GB]; (GB) (For US Only).
CHAMPION, Susan [GB/GB]; (GB) (For US Only).
GIBSON, Alex [GB/GB]; (GB) (For US Only).
GUILBERT, Bénédicte [FR/GB]; (GB) (For US Only)
Inventors: FORSTER, Alan, Michael; (GB).
KNOX, Peter; (GB).
MENDIZABAL, Marivi; (GB).
RICHARDSON, Timothy, Charles; (GB).
STOREY, Anthony, Eamon; (GB).
WILSON, Ian, Andrew; (GB).
CHAMPION, Susan; (GB).
GIBSON, Alex; (GB).
GUILBERT, Bénédicte; (GB)
Agent: PENNANT, Pyers; Stevens Hewlett & Perkins, 1 Serjeants' Inn, Fleet Street, London EC4Y 1LL (GB)
Priority Data:
97300383.3 21.01.1997 EP
Title (EN) LABELLED FACTOR XIIIa SUBSTRATES
(FR) SUBSTRATS DE FACTEUR XIIIa MARQUES
Abstract: front page image
(EN)A complex of a radiometal or paramagnetic metal ion with a metal chelating agent such as a diaminedioxime has attached thereto a substituent of formula -(Y)m-A-NHR, can function as a substrate for the fibrin-stabilising Factor XIIIa. The complex is useful for the diagnosis or therapy of thrombosis, embolism, atherosclerosis, inflammation or cancer.
(FR)La présente invention concerne un complexe formé d'un ion radiométallique ou d'un ion métallique paramagnétique et d'un agent chélateur métallique tel qu'une diaminedioxime, sur lequel est attaché un substituant répondant à la formule -(Y)m-A-NHR et qui peut fonctionner comme substrat pour le facteur XIIIa stabilisant la fibrine. Ce complexe est utilisé dans le diagnostic ou le traitement de la thrombose, de l'embolie, de l'athérosclérose, de l'inflammation ou du cancer.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)