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1. (WO1998029544) NOVEL PEPTIDE, NOVEL DNA, AND NOVEL ANTIBODY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/029544 International Application No.: PCT/JP1997/004585
Publication Date: 09.07.1998 International Filing Date: 12.12.1997
Chapter 2 Demand Filed: 24.07.1998
IPC:
A61K 38/00 (2006.01) ,A61K 48/00 (2006.01) ,C07K 14/47 (2006.01) ,C07K 16/18 (2006.01) ,C12N 15/85 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
Applicants: NABESHIMA, Youichi[JP/JP]; JP (UsOnly)
KUROO, Makoto[JP/JP]; JP (UsOnly)
SEKINE, Susumu[JP/JP]; JP (UsOnly)
IIDA, Akihiro[JP/JP]; JP (UsOnly)
KYOWA HAKKO KOGYO CO., LTD.[JP/JP]; 6-1, Ohtemachi 1-chome Chiyoda-ku Tokyo 100, JP (AllExceptUS)
Inventors: NABESHIMA, Youichi; JP
KUROO, Makoto; JP
SEKINE, Susumu; JP
IIDA, Akihiro; JP
Priority Data:
8/34787126.12.1996JP
9/20581531.07.1997JP
Title (EN) NOVEL PEPTIDE, NOVEL DNA, AND NOVEL ANTIBODY
(FR) NOUVEAU PEPTIDE, NOUVEL ADN ET NOUVEL ANTICORPS
Abstract:
(EN) A polypeptide having the activity of retarding aging; a DNA encoding this polypeptide; a method for breeding livestock with the use of this DNA; a recombinant DNA obtained by integrating this DNA into a vector; a transformant containing this recombinant; a process for producing the above polypeptide by using the transformant; an antibody capable of recognizing the polypeptide; a ligand for the polypeptide; a compound inhibiting the specific bond between the polypeptide and this ligand; a compound promoting the expression of the aging-retarding gene encoding the aging-retarding polypeptide; an oligonucleotide having a sequence consisting of 10 to 50 bases in the base sequence of the above DNA; and remedies for early aging, remedies for adult diseases, and aging resistors prepared with the use of the same.
(FR) L'invention concerne: un polypeptide susceptible de retarder le vieillissement; un ADN codant ce polypeptide; un procédé d'élevage de bétail faisant appel à cet ADN; un ADN recombiné obtenu par intégration de cet ADN dans un vecteur; un transformant contenant ce produit de recombinaison; un procédé permettant de produire le polypeptide susmentionné au moyen du transformant; un anticorps susceptible de reconnaître ledit polypeptide; un ligand destiné à ce polypeptide; un composé inhibant la liaison spécifique entre le polypeptide et ce ligand; un composé stimulant l'expression du gène retardant le vieillissement codant le polypeptide retardant le vieillissement; un oligonucléotide présentant une séquence constituée de 10 à 50 bases de la séquence des bases de l'ADN susmentionnée; et des remèdes permettant de lutter contre le vieillissement prématuré, contre des maladies de l'adulte, ainsi que des agents de résistance au vieillissement préparés à l'aide dudit polypeptide.
Designated States: AU, BG, BR, CA, CN, CZ, HU, IL, JP, KR, MX, NO, NZ, PL, RO, SG, SI, SK, UA, US, VN
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)