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1. (WO1998029452) ANTIBODIES SPECIFICALLY RECOGNISING A NITROSYLATED PROTEIN, METHOD OF PREPARATION, THERAPEUTIC AND DIAGNOSTIC USE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/029452 International Application No.: PCT/FR1997/002412
Publication Date: 09.07.1998 International Filing Date: 23.12.1997
Chapter 2 Demand Filed: 28.07.1998
IPC:
A61K 38/00 (2006.01) ,C07K 16/18 (2006.01) ,G01N 33/68 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants: CHAGNAUD, Jean-Luc[FR/FR]; FR (UsOnly)
GEFFARD, Michel[FR/FR]; FR (UsOnly)
VEYRET, Bernard[FR/FR]; FR (UsOnly)
VINCENDEAU, Philippe[FR/FR]; FR (UsOnly)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)[FR/FR]; 3, rue Michel Ange F-75015 Paris, FR (AllExceptUS)
Inventors: CHAGNAUD, Jean-Luc; FR
GEFFARD, Michel; FR
VEYRET, Bernard; FR
VINCENDEAU, Philippe; FR
Agent: BREESE-MAJEROWICZ; 3, avenue de l'Opéra F-75001 Paris, FR
Priority Data:
96/1620730.12.1996FR
Title (EN) ANTIBODIES SPECIFICALLY RECOGNISING A NITROSYLATED PROTEIN, METHOD OF PREPARATION, THERAPEUTIC AND DIAGNOSTIC USE
(FR) ANTICORPS RECONNAISSANT SPECIFIQUEMENT UNE PROTEINE NITROSYLEE, LEUR PROCEDE DE PREPARATION, LEUR UTILISATION THERAPEUTIQUE ET DIAGNOSTIC
Abstract:
(EN) The invention concerns a purified antibody specifically recognising a nitrosylated protein and more particularly a NO carrier such as albumin. These antibodies may be polyclonal-or monoclonal. The invention also concerns immunogens for preparing said antibodies and the pharmaceutical compositions containing them. The invention further concerns a method using said antibodies for detecting $i(in vitro) nitrosylated proteins in a biological sample.
(FR) La présente invention concerne un anticorps purifié reconnaissant spécifiquement une protéine nitrosylée et plus particulièrement un transporteur de NO comme l'albumine. Les anticorps de l'invention peuvent être polyclonaux ou monoclonaux. L'invention concerne aussi des immunigènes pour la préparation desdits anticorps, ainsi que les compositions pharmaceutiques comprenant lesdits anticorps. L'invention se rapporte également à un procédé de détection $i(in vitro) de protéines nitrosylées dans un échantillon biologique mettant en oeuvre lesdits anticorps.
Designated States: JP, US
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: French (FR)
Filing Language: French (FR)