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1. (WO1998029433) METHOD FOR SOLUBILIZATION AND NATURATION OF SOMATOTROPINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/029433    International Application No.:    PCT/US1997/024287
Publication Date: 09.07.1998 International Filing Date: 31.12.1997
Chapter 2 Demand Filed:    30.07.1998    
IPC:
C07K 14/61 (2006.01)
Applicants: MONSANTO COMPANY [US/US]; 800 North Lindbergth Boulevard, St. Louis, MO 63167 (US)
Inventors: STORRS, S., Bradley; (US).
TOU, Jacob, S.; (US).
BALLINGER, Jessica, Marie; (US)
Agent: WAACK, Janelle, D.; Arnold, White & Durkee, P.O. Box 4433, Houston, TX 77210 (US).
BOSCH, Henry, A.; Monsanto Services International S.A./N.V., Avenue de Tervuren, 270-272/Box 21, B-1150 Brussels (BE)
Priority Data:
60/034,808 31.12.1996 US
Title (EN) METHOD FOR SOLUBILIZATION AND NATURATION OF SOMATOTROPINS
(FR) PROCEDE DE SOLUBILIZATION ET NATURATION DES SOMATOTROPHINES
Abstract: front page image
(EN)A method for the solubilization and/or naturation of a somatotropin involves contacting a somatotropin with a detergent composition and water under conditions effective to obtain a naturated somatotropin, wherein the detergent composition may be a C10, C12, C16 or C18 acyl glutamate, a C10, C14 or C18 alkyl sulfate, an alcohol ethoxy sulfate, lauroyl ethylenediamine-triacetic acid (LEDA), a C10 to C18 linear alkyl benzene sulfonate, diphenyl disulfonate or an acyl amino acid.
(FR)La présente invention concerne un procédé utilisé pour la solubilisation et/ou la naturation d'une somatotrophine. Ce procédé implique la mise en contact d'une somatotrophine avec une composition détergente et de l'eau, dans des conditions effectives afin d'obtenir une somatotrophine naturée dans laquelle la composition du détergeant peut être un acyle glutamique en C10, C12, C16 ou C18, un alkyl-sulfate en C10, C14 ou C18, un éthoxy sulfate d'alcool, un lauroyl éthylenediamine - acide triacétique (LEDA), un alkyle benzène sulfonate linéaire en C10 à C18, un diphényle disulfonate ou un acide acylaminé.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)