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Pub. No.: WO/1998/028283 International Application No.: PCT/GB1997/003130
Publication Date: 02.07.1998 International Filing Date: 13.11.1997
Chapter 2 Demand Filed: 20.06.1998
IPC:
C07D 275/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
275
Heterocyclic compounds containing 1, 2-thiazole or hydrogenated 1,2-thiazole rings
04
condensed with carbocyclic rings or ring systems
Applicants: COX, Brian, Geoffrey[GB/GB]; GB (UsOnly)
GRAY, Thomas[GB/GB]; GB (UsOnly)
ZENECA LIMITED[GB/GB]; 15 Stanhope Gate London W1Y 6LN, GB (AllExceptUS)
Inventors: COX, Brian, Geoffrey; GB
GRAY, Thomas; GB
Agent: FAWKES, David, Melville; Avecia Limited Intellectual Property Group Hexagon House P.O. Box 42, Blackley Manchester M9 8ZS , GB
Priority Data:
9626570.720.12.1996GB
Title (EN) PROCESS FOR MAKING BENZISOTHIAZOLIN-3-ONES
(FR) PROCEDE DE FABRICATION DE BENZISOTHIAZOLINE-3-ONES
Abstract:
(EN) A process for making a 1,2-benzisothiazolin-3-one by cycling a bisamide precursor under alkaline conditions in the presence of oxygen or an oxygen-release compound in the presence of a nitrogen, sulphur or phosphorus nucleophile. Preferred nucleophiles are ammonia, primary, secondary and tertiary amines, amides, pyridines and quinolines.
(FR) L'invention a pour objet un procédé de fabrication de 1,2-benzisothiazoline-3-one. Ce procédé consiste à cycler un précurseur de bisamide dans des conditions alcalines en présence d'oxygène, ou un composé libérateur d'oxygène en présence d'azote, de soufre ou de nucléophile de phosphore. Les nucléophiles préférés sont l'ammoniac; les amines primaires, secondaires et tertiaires, les amides, les pyridines et les quinoléines.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU
African Regional Intellectual Property Organization (ARIPO) (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)