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Machine translation
1. (WO1998028000) STABILIZERS FOR LYOPHILIZED VACCINES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/028000    International Application No.:    PCT/US1997/023668
Publication Date: 02.07.1998 International Filing Date: 18.12.1997
Chapter 2 Demand Filed:    20.07.1998    
IPC:
A61K 9/00 (2006.01), A61K 39/13 (2006.01), A61K 39/165 (2006.01), A61K 39/20 (2006.01), A61K 39/25 (2006.01), A61K 39/29 (2006.01), A61K 47/26 (2006.01), A61K 47/42 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
VOLKIN, David, B. [US/US]; (US) (For US Only).
BURKE, Carl, J. [US/US]; (US) (For US Only).
SHEU, Su-Pi [--/US]; (US) (For US Only)
Inventors: VOLKIN, David, B.; (US).
BURKE, Carl, J.; (US).
SHEU, Su-Pi; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
60/033,565 20.12.1996 US
9702820.3 12.02.1997 GB
Title (EN) STABILIZERS FOR LYOPHILIZED VACCINES
(FR) STABILISANTS POUR VACCINS LYOPHILISES
Abstract: front page image
(EN)Vaccine stabilizers, vaccine formulations and lyophilized vaccines with enhanced thermostability are disclosed. The vaccine formulations comprise an increased amount of a 6-carbon polyhydric alcohol (such as sorbitol), an increased amount of a disaccharide (such as sucrose) and an amount of a physiologically active buffer to adjust the pH from about 6.0 to about 7.0.
(FR)L'invention concerne des stabilisants pour vaccins, des formulations de vaccins et des vaccins lyophilisés ayant une stabilité thermique accrue. Les formulations de vaccins comprennent une plus grande quantité d'un alcool polyhydrique à 6 carbones (tel que le sorbitol), une plus grande quantité d'un disaccharide (tel que le sucrose) et une certaine quantité d'un tampon physiologiquement actif destiné à régler le pH sur une valeur comprise entre 6,0 et 7,0 environ.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, GW, HU, ID, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)