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Machine translation
1. (WO1998017689) IL-12 GENE EXPRESSION AND DELIVERY SYSTEMS AND USES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/017689    International Application No.:    PCT/US1997/018779
Publication Date: 30.04.1998 International Filing Date: 10.10.1997
Chapter 2 Demand Filed:    08.05.1998    
IPC:
A61K 38/00 (2006.01), C07K 14/54 (2006.01)
Applicants: VALENTIS INC. [US/US]; 8301 New Trails Drive, The Woodlands, TX 77381-4248 (US) (For All Designated States Except US).
SYNTEX (U.S.A) INC. [US/US]; 3401 Hillview Avenue, P.O. Box 10850, Palo Alto, CA 94303 (US) (For All Designated States Except US).
NORDSTROM, Jeff [US/US]; (US) (For US Only).
FREIMARK, Bruce [US/US]; (US) (For US Only).
DESHPANDE, Deepa [IN/US]; (US) (For US Only)
Inventors: NORDSTROM, Jeff; (US).
FREIMARK, Bruce; (US).
DESHPANDE, Deepa; (US)
Agent: WARBURG, Richard, J.; Lyon & Lyon LLP, Suite 4700, 633 West Fifth Street, Los Angeles, CA 90071-2066 (US).
MOON, Donald, Keith; Brewer & Son, Quality House, Quality Court, Chancery Lane, London WC2A 1HT (GB)
Priority Data:
60/028,676 18.10.1996 US
Title (EN) IL-12 GENE EXPRESSION AND DELIVERY SYSTEMS AND USES
(FR) EXPRESSION DU GENE IL-12, SYSTEMES D'APPORT ET UTILISATIONS
Abstract: front page image
(EN)Plasmid expression systems for delivery of DNA coding sequences to a mammal are described which provide expression of multiple coding sequences from a single plasmid. Also desribed are particular lipid/DNA delivery systems having advantageous characteristics of size, charge ratio, and proportion of supercoiled DNA, and methods of preparing and using such delivery systems for treatment.
(FR)L'invention concerne des systèmes d'expression plasmidiques destinés à apporter des séquences codantes d'ADN à un mammifère, qui permettent l'expression de multiples séquences codantes à partir d'un seul plasmide. L'invention concerne également des systèmes d'apport de lipides/d'ADN particuliers, ayant des caractéristiques avantageuses en ce qui concerne la taille, le rapport des charges et le pourcentage d'ADN superenroulé, ainsi que des méthodes permettant de préparer et d'utiliser lesdits systèmes d'apport à des fins thérapeutiques.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)