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1. (WO1998017677) IMPROVEMENTS IN SOLID-PHASE SYNTHESIS OF PEPTIDES AND RELATED COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/017677    International Application No.:    PCT/AU1997/000711
Publication Date: 30.04.1998 International Filing Date: 24.10.1997
Chapter 2 Demand Filed:    16.04.1998    
IPC:
C07K 1/04 (2006.01)
Applicants: THE UNIVERSITY OF QUEENSLAND [AU/AU]; Brisbane, QLD 4072 (AU) (For All Designated States Except US).
ENGLEBRETSEN, Darren [AU/NL]; (NL) (For US Only)
Inventors: ENGLEBRETSEN, Darren; (NL)
Agent: SANTER, Vivien; Griffith Hack, 509 St. Kilda Road, Melbourne, VIC 3004 (AU)
Priority Data:
PO 3240 24.10.1996 AU
Title (EN) IMPROVEMENTS IN SOLID-PHASE SYNTHESIS OF PEPTIDES AND RELATED COMPOUNDS
(FR) AMELIORATIONS APPORTEES A LA SYNTHESE EN PHASE SOLIDE DE PEPTIDES ET DE COMPOSES APPARENTES
Abstract: front page image
(EN)The invention relates to spacers for use in solid-phase synthesis of peptides and peptide-related compounds, in which a spacer construct is used to ensure that the target peptide or peptide-related compound is at a distance equivalent to at least 5-15 amino acids from the solid support. Constructs of the invention are particularly applicable to the synthesis of strongly hydrophobic peptide, which are otherwise difficult, if not impossible to purify and analyse. The constructs and methods of the invention are also applicable to synthesis of peptide nucleic acids.
(FR)L'invention concerne des espaceurs utilisés dans la synthèse en phase solide de peptides et de leurs composés apparentés. On utilise une construction d'espaceur pour faire en sorte que le peptide cible ou le composé apparenté cible soit séparé du support solide par une distance égale ou supérieure à 5-15 acides aminés. On peut notamment utiliser les constructions de la présente invention dans la synthèse d'un peptide fortement hydrophobe, qu'il serait difficile, voire impossible, de purifier et d'analyser. Les constructions et les méthodes faisant l'objet de cette invention peuvent également être appliquées à la synthèse d'acides nucléiques peptidiques.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)