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1. WO1998017655 - METALLOPROTEINASE INHIBITORS

Publication Number WO/1998/017655
Publication Date 30.04.1998
International Application No. PCT/GB1997/002891
International Filing Date 20.10.1997
Chapter 2 Demand Filed 02.03.1998
IPC
C07D 295/185 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
16acylated on ring nitrogen atoms
18by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
182Radicals derived from carboxylic acids
185from aliphatic carboxylic acids
C07D 295/26 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
22with hetero atoms directly attached to ring nitrogen atoms
26Sulfur atoms
CPC
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 17/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
06Antipsoriatics
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A61P 19/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
A61P 27/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
Applicants
  • BRITISH BIOTECH PHARMACEUTICALS LIMITED [GB]/[GB] (AllExceptUS)
  • BECKETT, Raymond, Paul [GB]/[GB] (UsOnly)
  • MARTIN, Fionna, Mitchell [GB]/[GB] (UsOnly)
  • MILLER, Andrew [GB]/[GB] (UsOnly)
  • TODD, Richard, Simon [GB]/[GB] (UsOnly)
  • WHITTAKER, Mark [GB]/[GB] (UsOnly)
Inventors
  • BECKETT, Raymond, Paul
  • MARTIN, Fionna, Mitchell
  • MILLER, Andrew
  • TODD, Richard, Simon
  • WHITTAKER, Mark
Agents
  • WALLS, Alan, J.
Priority Data
9621814.419.10.1996GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METALLOPROTEINASE INHIBITORS
(FR) INHIBITEURS DE METALLOPROTEASE
Abstract
(EN)
Compounds of formula (I), wherein n, V, R1, R2, R3 and R4 are as defined in the specification are matrix metalloproteinase inhibitors.
(FR)
L'invention concerne des composés de formule (I) constituant des inhibiteurs de métalloprotéase matricielle, formule dans laquelle n, V, R1, R2, R3 et R4 sont tels que définis dans la description.
Also published as
NZ334711
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