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1. WO1998017274 - THROMBIN INHIBITORS

Publication Number WO/1998/017274
Publication Date 30.04.1998
International Application No. PCT/US1997/018682
International Filing Date 20.10.1997
Chapter 2 Demand Filed 22.05.1998
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07D 471/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07K 5/078 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
06Dipeptides
078the first amino acid being heterocyclic, e.g. Pro, His, Trp
C07K 5/097 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
08Tripeptides
097the first amino acid being heterocyclic, e.g. Pro, His, Trp, e.g. thyroliberin, melanostatin
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 7/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07K 5/06139
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
06Dipeptides
06139with the first amino acid being heterocyclic
C07K 5/0821
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
08Tripeptides
0821with the first amino acid being heterocyclic, e.g. His, Pro, Trp
Applicants
  • MERCK & CO., INC. [US]/[US] (AllExceptUS)
  • COBURN, Craig [US]/[US] (UsOnly)
  • KOLATAC, Christine [US]/[US] (UsOnly)
  • RUSH, Diane, M. [US]/[US] (UsOnly)
  • VACCA, Joseph, P. [US]/[US] (UsOnly)
Inventors
  • COBURN, Craig
  • KOLATAC, Christine
  • RUSH, Diane, M.
  • VACCA, Joseph, P.
Common Representative
  • MERCK & CO., INC.
Priority Data
60/029,05324.10.1996US
9624319.122.11.1996GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) THROMBIN INHIBITORS
(FR) INHIBITEURS DE THROMBINE
Abstract
(EN)
A compound which inhibits human thrombin and which has structure (a) such as (b).
(FR)
L'invention concerne un composé inhibant la thrombine humaine, possédant la structure (a) telle que (b).
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