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1. (WO1998017272) USE OF ANTIBODIES TO SIALIDASE AS ANTI-INFECTIOUS AGENTS AND ANTI-INFLAMMATORY AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/017272    International Application No.:    PCT/US1997/018728
Publication Date: 30.04.1998 International Filing Date: 21.10.1997
Chapter 2 Demand Filed:    19.05.1998    
IPC:
A61K 31/35 (2006.01), A61K 31/70 (2006.01), A61K 31/7012 (2006.01), A61K 31/7028 (2006.01), A61K 39/21 (2006.01), A61K 39/395 (2006.01), A61P 29/00 (2006.01), A61P 31/18 (2006.01)
Applicants: CROSS, Alan, S. [US/US]; (US).
STAMATOS, Nicholas, M. [US/US]; (US).
GOMATOS, Peter, J. [US/US]; (US)
Inventors: CROSS, Alan, S.; (US).
STAMATOS, Nicholas, M.; (US).
GOMATOS, Peter, J.; (US)
Agent: MARSH, James, H., Jr.; Shook, Hardy & Bacon L.L.P, One Kansas City Place, 1200 Main Street, Kansas City, MO 64105-2118 (US)
Priority Data:
08/736,236 23.10.1996 US
Title (EN) USE OF ANTIBODIES TO SIALIDASE AS ANTI-INFECTIOUS AGENTS AND ANTI-INFLAMMATORY AGENTS
(FR) UTILISATION D'ANTICORPS CONTRE LA SIALIDASE EN TANT QU'AGENTS ANTI-INFECTIEUX ET ANTI-INFLAMMATOIRES
Abstract: front page image
(EN)Sialic acids have the ability to prevent hyposialylation of cells as competitive inhibitors of endogenous sialidase. It is now also possible to develop antibodies to mammalian sialidase that significantly reduce influx of neutrophils into inflammatory sites.
(FR)Les acides sialiques ont la capacité d'empêcher l'hyposialylation des cellules en tant qu'inhibiteurs compétitifs de la sialidase endogène. Il est maintenant possible également de mettre au point des anticorps contre la sialidase mammalienne qui réduisent de manière significative l'afflux de neutrophiles sur les sites inflammatoires.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)